Patrick Collison — Why Silicon Valley's most talented should leave

0:48

Today I have the pleasure of speaking with Patrick  Collison, CEO of Stripe. Patrick, first question.

0:54

You have an excellent compilation of advice on  your blog for people 10 to 20.

0:54

You say there, that once you turn 35, you'll write some for people  in their 20s.

0:59

What advice do you have for us now, the people in our 20s? When is it coming?

1:05

Patrick Collison 00:22 I haven't really thought about that.

1:09

The  one piece of advice I've been wondering about recently is this: I said that people  in their teens should go to San Francisco.

1:24

I wonder if people in their 20s shouldn't go to  San Francisco.

1:24

That advice was a generalization.

1:31

There's a significant set of people who should  go to San Francisco.

1:31

But there is a set of career paths that people ought to pursue and  would derive most fulfillment from pursuing, that are also really valuable for the world,  that require accumulating a lot of expertise and studying a domain in tremendous depth.

2:02

I think San Francisco valorizes – this is also San Francisco's great virtue.

2:11

San  Francisco valorizes striking out on your own, iconoclastically dismissing the received wisdom.

2:17

It praises the founding archetypes and lore of Steve Jobs and Bill Gates and all the rest.

2:28

I'm way less successful than those people, but to some extent, Stripe, in as much as it fits  a pattern, is an instance of that pattern.

2:33

That's great, I'm happy that this phenomenon exists  in the world.

2:39

But the world needs lots of other things.

2:49

And I don't think San Francisco,  using San Francisco as a kind of a metonym for a cultural orientation, encourages the  pursuit of really deep technical knowledge.

3:10

We're recording this in South San Francisco,  which is most noteworthy in the corporate world for being the headquarters of Genentech.

3:18

Genentech was co-founded by Bob Swanson and Herb Boyer.

3:27

They produced cheap insulin  for the first time with recombinant DNA.

3:27

Like Herb Boyer couldn't have done that at age 23.

3:35

Herb Boyer first had to accumulate all of the knowledge and the skills required to be able to  invent that over the course of a multi-decade career.

3:47

I don't know what age he was when he  finally went and invented it, but he was not in his 20s.

3:52

I feel like San Francisco doesn't  culturally encourage one to become Herb Boyer.

4:02

Or yesterday, at the time of recording this  podcast, Patrick Hsu, one of the co-founders of Arc, which maybe we'll speak about later  in the show.

4:07

This is a biomedical research organization we started a few years ago.

4:12

He  announced this new phenomenon of bridge editing, which is a new recombinase where you can insert  DNA into a genome.

4:22

It's pretty early, but it might turn out to be quite consequential.

4:31

In order to  do something like that, you have to study for a long time and acquire a lot of technical skills.

4:38

I don't quite know how to synthesize it yet, but as I think about advice for people in their 20s,  I'm not going to normatively pretend to know or presume in which direction one should go in  life.

4:55

Obviously, there are successful examples of basically every strategy.

5:03

I'm really glad  that you're doing what you're doing at what age? 23. 23. So that's...

5:12

A podcast, I’ve got a podcast.

5:12

I think information dissemination is a really valuable thing in the  world.

5:19

The guy, who, last time I heard, was in the lead for Nat's Scroll Prize, learned  about it, listening to your podcast.

5:27

Increasing the catalytic surface area of certain kinds of  information is a valuable thing in the world, so I'm very glad you're doing the podcast.

5:43

Anyway, I don't presume to know what people should do with their lives.

5:48

But in as much as I  was trying to give advice, especially if they're reading my advice and not someone else's, maybe  they're thinking about career paths that look directionally like mine, I think my advice might  be: "Maybe you should do something like what I did or I'm trying to do.

6:06

But there are other paths  as well.

6:06

A lot of really important inventions in the world and a lot of the things that I'm most  happy are happening, require a very different trajectory from mine.

6:19

There are counterfactual  versions of my life, where I pursued that path and who knows how well it would have worked."

6:25

Last point is that San Francisco is very status oriented.

6:32

Everything is status oriented, so the  previous statement is kind of tautological.

6:32

I feel like in San Francisco the entrepreneurs  are held in excessively high regard.

6:40

Look, I like entrepreneurs as a group in the world.

6:51

All  the companies built in Stripe I think are great.

7:03

But there's a strange emphasis placed  on entrepreneurship in San Francisco, that should not be people's only fixation.

7:07

What I like about this and what I admire about you is that you have this sense of contrarianism – the  way you often challenge what people are expecting to hear from you in a given moment.

7:19

You just  really want to tell them the opposite.

7:19

When EA was a little more popular, you were talking about the  important problems, and when it was down in its depths, you were like: "Hey guys, pay attention."

7:31

But on this particular piece of advice… Michael Nielsen says that every field in science  has way too many adherents or way too few.

7:36

The market is almost never in the right equilibrium  and I think something like that might be the case for EA.

7:50

I think reflexive contrarianism for  the sake of it is also tired.

7:50

If you're just contrarian to the prevailing mood, then you're  following the prevailing mood but with a sign bit inversion.

8:05

I don't endorse that either.

8:05

The herd is a really powerful phenomenon.

8:13

One of the learnings of my adult life has  been something, that everyone knows and says or frequently hears, that you should  be very wary of following the prevailing tides and moods and whims and everything.

8:24

But it's freaking hard to do in practice.

8:29

So what practically does that look like to hone  your craft in any of these disciplines that take a long time?

8:33

You've spoken and tweeted about  some of the problems with modern universities.

8:37

Is that still the de facto path if you want  to be the great biologist at Arc or something?

8:46

In many domains, I don't know.

8:46

For example  I have no facility with or experience with doing things in hardware, which is not  a small domain.

8:47

If you wanted to become a super skilled practitioner there, what's the  best career path? I don't know.

8:59

Maybe it's to drop out and join SpaceX or something.

9:07

I'm  not necessarily endorsing pursuing the most establishment and credential oriented path.

9:18

People should try to find the gradient of maximal learning in whatever it is they care  most about.

9:23

The question then is what that is.

9:32

For biology, not that I'm a biologist, but it is  very clear that in order to do really good work, there are a lot of "bench" skills one has  to acquire and there is a lot of actual specific knowledge.

9:50

Any kind of life wasn't  designed with neat fundamental principles the way that maybe physics was.

10:02

A lot of it is  obviously evolved and contingent and messy and complicated and all the rest.

10:07

So there  is a lot of specific factual stuff to learn.

10:12

For those two reasons, there are very few  successful pure autodidacts in biology.

10:25

In virtually every case that I'm aware of, at  some point, you have to get direct experience in and with a top lab, where you're seeing  how people actually do it in practice.

10:33

This also ties back to what we were discussing  previously: your question about the founders and what they learn from each other and so on.

10:46

There's an interesting book, Apprentice to Genius, that follows three generations of scientists.

10:54

So someone who mentored somebody else, who in turn mentored another scientist.

11:01

And they're  all extremely successful.

11:01

The book is this description of what they all did, but also this  reflection on: "What is it that was transferred?" .

11:18

For example, one of the most important and subtle  questions in science is problem selection.

11:18

How do you choose what to work on?

11:26

No one tells  you what to do.

11:26

And you do have to answer this question multiple times.

11:32

With a company, in  some sense, you have to decide it once, and then it's an iterative process from there.

11:38

Whereas in  science, you're frequently pursuing completely new problems.

11:42

You need to choose something that's  sufficiently important and hard, so that it would be important if you succeeded, but it also  mustn't be so complex that progress becomes unachievable.

11:56

This is what mentees learn  from their mentors according to the book.

12:02

Another thing the book talks about is learning  about high standards and what they actually are.

12:12

When I talk to people in other domains,  I hear very frequently, that when they worked with X person or Y organization or in Z  environment, they learned what great actually is.

12:28

And that just permanently changed their sense  for what their own standard for their work ought to be.

12:34

So one version of what people  in their 20s should do is get some ideas for domains you're interested in, but then figure  out where can you learn the highest standards, where are the highest standards embodied, and  where can you go and experience that first hand.

12:58

Before we get back to Stripe and Arc Institute,  I want to touch on the Parker study for a second.

13:02

There's a view that says: "If we  improve the NIH 10% or whatever percent, are we really making a dent in the fact that ideas  are getting harder to find over time?

13:09

And how much of a difference do institutions make anyways?

13:13

Is  it just about a number of researchers and how many people in society you can put into research?

13:19

It's  not like Singapore can get a much more effective scientific institution that lets it compete with  America in science by following this approach.

13:28

What's wrong with that intuition?

13:28

Noah Smith and others have talked about, I can't remember the term he used, something  like “moneyism”. He had a funny phrase.

13:32

It pertains to the presumption that there is  some constant elasticity between investment in some particular outcome, like building a  semiconductor factory in Arizona or a new bridge, and the outcome of the factory or the bridge.

13:55

First of all, the conversion rate between those inputs and the output is not a cosmological  constant.

14:03

Maybe any of these things could be done for half or a tenth of the cost.

14:11

Secondly, there  are even deeper questions as to, is it possible at all?

14:21

What else would have to change for it to  be possible?

14:21

What are the other constraints?

14:21

By talking about these things in funding and  dollar terms, you're making the implicit assumption that the only relevant constraint  is the financial one, where in practice, maybe it's permits or labor shortages or other things.

14:35

In the context of the NIH and science and R&D, I'm really skeptical of this approach being  brought to bear, where we can just talk about the amount that we're spending on R&D and think that  that's implicitly a useful measure of the output.

15:04

To a fairly close approximation, there were  around 1% as many practicing professional scientists in the US pre-World War II as  there were post-World War II or say even 1950.

15:20

The other epiphenomena in papers or patents and so  forth tend to follow pretty similar ratios.

15:20

We got a lot of pretty good stuff in the first half  of the century.

15:31

Despite increasing the amount that we spend between two and maybe slightly more  than two orders of magnitude it's not clear to me that there is a direct linear relationship between  spending and output.

15:51

When analyzing the NIH or how we should pursue any of this stuff, I try to get  more concrete and tactile and think, what would success here look like?

16:07

What is happening today at  the microscale?

16:07

What are the actual problems?

16:07

What could success look like at the microscale?

16:16

What might it look like to scale that up?

16:23

One example of that, we ran a survey of the Fast  Grants grant recipients after Fast Grants asking about their normal work, and not about anything to  do with Fast Grants itself.

16:30

We asked them if they had flexible funding, that is to say if they could  direct their current research dollars however they wanted how much their associated research program  would change.

16:49

And we gave them three options: not much, a little, and a lot.

16:53

Four out of  five(79%) said that their research agenda would change a lot if this constraint was removed.

17:00

Asking: "Should the NIH funding level be X or 1. 1X or 1. 2X or whatever?"

17:10

seems to me like a bad  way to analyze this question as compared to: "How bound and constrained should an NIH grantee  be in choosing their research agenda?"

17:16

Maybe their judgment is way better than that of the  committees, not saying it is, but who knows?

17:29

Maybe there's a 5X improvement to be generated  just by making that one switch?

17:29

I'm very skeptical of these financially-oriented frameworks.

17:37

Maybe financial is not the right word for it, but just trying to map inputs to outputs  is the framing, which you're using to compare the pre-World War II inputs to what's happening  now.

17:49

If it was particular to the scientific institutions, you'd expect, for example, that  things that are disconnected from the NIH-specific structures would show different trends.

18:00

You've  talked a lot about the fact that it's getting harder to find impactful papers.

18:04

Sector through  sector, it's not like NIH is running Moore's Law progress, right?

18:09

But even there you see that you  need exponentially more researchers to keep up the same level of progress.

18:13

It does seem important to  have these "level effects", that are one-time, in the case of something like COVID happens, where we  say: "Yeah, we need that level-effect" right now."

18:23

But if we're framing it in terms of hundreds  of years from now, I wonder if these events are going to be a thing that increases growth  rates, which is a sort of framing that is also applied when talking about progress.

18:32

Does that make sense in that context, when all sectors are seeing slowdowns,  which seem consistent with how the economy and science progresses over time?

18:42

“I don't know” is the short answer. It's really puzzling.

18:45

The constancy of US  GDP growth is one of the weirdest things.

18:56

I don't know if I've got an explanation for it.

18:56

An obvious thing to do would be to shrug and say: "OK, well, it's overdetermined, and that's just  how countries work."

19:02

But you can look at other countries, where it's manifestly not the case.

19:07

What is it that's weird and special about the US?

19:13

The thing that I wonder about in a lot of these  cases is: you could get many of the observed system phenomenon characteristics, if we weren't  actually adding productive capacity.

19:19

That's a simple way to explain a lot of it, in that if  you're just adding exponentially more unproductive capacity, then on a stylized level, a lot of this  stuff would just fall out of it.

19:32

Now, I'm not saying that we're necessarily doing that, but it  could be that maybe we're making them...

19:39

There's lots of ways where that could be quite effectively  going on, even if it's not the case that the marginal people or things or organizations  themselves are bad.

19:58

It's just how the components interact.

20:03

But the fact that you could get these  exponentially diminishing returns through the addition of ever more nonproductive capacity  makes me not persuaded that the low-hanging case is necessarily true, and gives some  weight to the prospect that it's fundamentally structural, cultural, or organizational.

20:26

Just to give a micro example there, and it's a very basic and an obvious one, it's interesting  to compare the SpaceX R&D budget and the NASA R&D budget and to actually look at those two time  series together.

20:48

Maybe we're just returning to the financial point again, but it seems pretty  clear that the trajectory of NASA's efficacy has not fully followed the trajectory of its inputs.

21:13

Yeah, although the point about: "the marginal inputs we put into science have not been  as effectively used as what was before".

21:26

The 1X then was a 1X of much higher quality, than  100X now.

21:26

It's not clear what you do to fix that.

21:31

If it's just a case, that there's a limited  amount of John von Neumanns in your society, that are part of the pre-World War II 1X,  it's not like we can just put 100X more John von Neumann-type physicists into science.

21:40

If the binding constraint is the number of John von Neumann's, then yes, that's bad news, I  guess.

21:45

There's not a lot we can do on the margin.

21:51

But I'm not sure that it is.

21:51

I keep going back  to the cultural and sociological point.

21:51

Gerty and Carl Cori, they ran a lab at the University of  Washington, St. Louis.

22:00

And six of their students, if I recall correctly, went on to win  Nobel prizes.

22:07

They had a well-known lab, they got good students, but they weren't the most  prestigious lab in the world.

22:13

It's not like they got to cherry-pick every year the single most  promising person, so something was going on there.

22:24

There's a book about it, which tries to  get into this a little bit.

22:24

I don't know if I can figure out quite what it was.

22:30

There was also  some good fortune, where they got into molecular biology at a good time, but I think there were  these "hopeful data points".

22:35

Again, they were extremely brilliant people, but the thing that  distinguished them and their students was not that they were these seven "sigma-Martians", it was  rather that they found organizational structures and cultural practices that really worked.

22:54

Those  are, at least in principle, more replicable.

22:59

Now, you might still say: "OK, fine,  in theory.

22:59

But how do you actually do that?"

23:02

That's the big open question.

23:02

OK, that's a great point to talk about, Arc institute.

23:09

I think you just answered  this question but still: It's not exactly like biology research is, it's something that  society has neglected.

23:16

So what's the theory of change here?

23:21

Is it just a story similar to Stripe?

23:21

In that, if you get the right people, there's tens of billions of dollars of biology funding.

23:26

Getting the right people, the right culture and right education is what it takes, right?

23:29

Even though there are lots of scientists and lots of universities, there's a lot  of homogeneity today in how science, and in particular, how biomedical science  is pursued, where basic research is done in an academic context before there's any  commercialization prospect in sight.

23:47

I don't know that this model is necessarily a bad one.

23:55

Certainly, we're not claiming that it's a bad one.

24:00

Construct of universities, labs, PI — a principal  investigator running the lab, who applies for grants primarily to the NIH, maybe supplemented  by other sources, grants reviewed by committees with "study sections", as they call them, with  pretty rigid scoring criteria and so on — that is the structure and it seems suboptimal to me.

24:23

Homogeneity is bad in basically any ecosystem, especially ecosystems where you're producing  or seeking tail outcomes.

24:32

And we thought that, for a variety of reasons, from first principles,  other models should be possible.

24:42

We had specific ideas as to how one particular model might be a  good idea and complementary to the status quo.

24:55

In very short terms, what's different  about Arc is: one, scientists are funded themselves to pursue whatever they want.

25:03

So it's curiosity-driven research, whereas NIH grants are given for projects.

25:07

Second,  we build a lot of in-house infrastructure, so that scientists can draw upon other platforms  and capabilities that they don't have to build and maintain themselves.

25:18

Whereas, in the standard  university academic context, scientists would virtually always have to do that in-house.

25:25

Because  of the natural scale constraints on any given lab, that effectively circumscribes the ambition  of a possible research program.

25:30

And thirdly, we try to provide career paths for people to  remain in science if they don't want to become principal investigators, whereas the university  structure commingles the training purpose of academia with the execution — the people who  are doing the work there are typically the grad students and the postdocs, who are themselves, at  least nominally, on the career path of eventually becoming principal investigators.

26:06

There are lots  of people who, for all sorts of different very valid reasons, love science and the pursuit of  research, but don't want to be a manager running a lab, choosing their own research programs, and  dealing with all of the overhead and typically grant applications that are concomitant with that.

26:26

With Arc, we have a real emphasis on hiring scientists to finish their postdocs, finish grad  school, who know that that's what they want to do in their lives.

26:37

And again, it isn't really  a career path for them today.

26:37

One of the things that's really exciting about the discovery,  that we mentioned, that came out yesterday, this new bridge editing technology, is: that  work was led by one of senior scientists, who had finished his postdoc.

26:50

It's not clear  to me that he wanted to become a PI, but he loved science, and he's an amazing researcher,  so he's able to go and have that career at Arc.

27:12

In addition, the prospect of mobile elements  being usable in this way for genomic insertion, whatever, — that's a pretty speculative, out  there thing.

27:21

Had he applied to the NIH to go and pursue that?

27:26

He didn't, so I don't  know what the outcome would have been.

27:30

But Jennifer Doudna's work was, if  I recall correctly, funded by DARPA, because her CRISPR NIH applications were rejected.

27:37

Katalin Kariko's NIH applications for mRNA vaccine work were famously rejected.

27:47

It at least seems  very plausible that it wouldn't have worked out.

27:58

All these things are random, and I can't make  any definitive claims about what would have counterfactually happened.

28:02

But it seems plausible  to me that this thing announced yesterday wouldn't have happened or would have been less  likely to happen in a different environment.

28:12

When we think forward 10 or 20 years, this  specific line of research, where you understand the effects of the genetic architecture on  different traits, and you can edit, invert, insert the DNA arbitrarily.

28:27

You've solved cell  anemia — you've done the obvious things. What does that lead to?

28:34

What are you excited about?

28:34

The thing that is really interesting about it is using it as a new kind of telescope: when  people hear about CRISPR, there's an obvious and legitimate excitement around using this to  cure things directly in the body, as a kind of therapeutic.

28:55

You can also use CRISPR to try  to figure out what's going on in cells and in cell cultures in a structured way.

29:03

So the body is  interesting in that it has this switchboard, akin to DJ’s with those fancy mixing sets, of 20,000  genes.

29:14

And with CRISPR, you can systematically go and perturb each gene one by one, mashing all the  keys in sequence, and try to figure out what the effects of perturbing this versus that are.

29:31

If you  do that in a cell culture, where you can subject the cells to some stressor or treatment, you can  see differentially how different perturbations affect different cell outcomes.

29:45

Or you can use  it for synthetic data generation more broadly, where you could perform all these perturbations,  then sequence and see what's happening in the cells and so forth.

29:55

And single cell sequencing has  come a long way.

29:55

Anyway, the point is, there's a lot you can do with gene editing for discovery  and for data generation in the broadest sense.

30:12

That's really compelling, because a lot of  diseases are "complex" in the field's jargon.

30:12

Yes, they're complex in the colloquial sense, but  they're specifically complex in that they're not infectious.

30:25

They're not just some pathogen  getting into you.

30:25

And they're not monogenic, like Huntington's, where it's one specific  mutation.

30:31

Instead, they are some combination of environmental factors, but maybe some  genetic factors as well — they are somewhere in between.

30:40

These include most autoimmune  diseases, most cancers, to some extent cardiovascular disease and neurodegenerative  disease — the big ones we haven't yet solved.

30:59

Coming back to functional genomics technologies,  what's interesting is trying to figure out how it is that the genetic component of those  diseases works.

31:04

And even if that's only a small contributor, it can potentially shine light on  what the general pathway is.

31:12

So the question would be, and this is speculative, none of this has  actually happened: "By figuring out the genetic interactions between genes and, say, Alzheimer's,  can you figure out how Alzheimer's arises, which we don't understand today?"

31:31

Then once you  understand how Alzheimer's arises, maybe you can use conventional technologies to figure out how  to inhibit or modulate those pathways.

31:35

That's what we're really excited about from a functional  genomics standpoint.

31:49

There's an AI angle as well that we could talk about if you want.

31:54

How do you think about the dual use possibilities of biotech?

31:59

I am sympathetic with  the idea that if you think of prior technology, like Google search or even the computer  itself, you could forecast in advance, like: "Oh, this has all this dual use stuff."

32:09

But for some reason, history has been kind to us.

32:14

The meta-lesson here is: “Keep doing science.

32:14

” With biotech, we don't have to go into specifics here, but are there specific things you can think  of with this specific technology?

32:23

You can imagine some nefarious things.

32:27

How do you think about  that?

32:27

Why not focus, let's say, on ameliorating the risks first or something like that?

32:33

I don't think that the binding constraint on harmful use of biotechnology or bioweapons  today is pure biological capabilities.

32:43

If some set of incredibly capable, intelligent people  wanted to cause tremendous harm, presumably with pathogens or with something biological, they  wouldn't necessarily need to invent anything new.

33:04

They would just need to apply currently known  techniques in a malevolently directed fashion.

33:11

There are some concerns and risks with respect  to things that don't invent new technologies, but do make them more accessible.

33:18

The question  is, what would the effect on the world be if there was a sufficiently sophisticated  LLM that could help anybody synthesize and disperse smallpox?

33:37

I don't know laws of  physics that prohibit such an LLM existing — I presume they don't.

33:43

Would the world be fine  if such an LLM was widely distributed? Maybe, but maybe not.

33:50

So there is that threat factor,  but my point is: I don't think knowledge at the frontier of biology is the relevant margin here.

33:57

If we take this seriously, we don't need crazy AI risks to motivate this.

34:09

The world is perfectly  capable of originating really severe pandemics and pathogens itself, plus all the other diseases  that are not pathogenic.

34:15

So we got other problems.

34:22

Whether we care about the possible dual use  harms you just mentioned, or we just care about things that already exist, to ameliorate both of  those, we do need enhancement of our capabilities.

34:36

There are a lot of biological problems that we  don't know how to solve today.

34:36

In that respect, if one were to do what you're proposing and  try to advance the defensive side of this, I don't know that, what one would do, would  necessarily be that different.

34:49

Because there are just fundamental capabilities that we would  presumably need to have, that we don't have today.

35:02

By trying to solve current human diseases, you're  probably also pursuing something pretty close to the best steps to solve the potential diseases  that malicious actors could cause in the future. That makes sense.

35:14

Zooming out  from bio risk in particular, how are you thinking about AI these days?

35:19

Everyone has to be highly perplexed, in the sense that the verdict that  one might have given at the beginning of 2023, 2021, back, say, the last eight years —  we're recording this pretty close to the beginning of 2024 — would have looked pretty different.

35:37

Maybe Gwern might have scored the best from 2019 or something onwards, but broadly speaking,  it's been pretty difficult to forecast.

35:51

So the basic position to a first order has to be some  degree of humility.

36:00

As your blog post identifies, the big question right now is: "To what  degree scaling laws hold?"

36:07

And if they hold, then what exactly is it that we're, asymptoting is  maybe a presumptuous word, it's not an asymptote, but what is it, that we're approaching?

36:23

We  don't necessarily know the shape of that thing, whatever it is.

36:29

How one should feel ought to be  very sensitive to the exact parameters of those curves, and I don't think anyone knows what  the true value of those parameters actually are.

36:51

It's clearly going to be important,  is already important today, it has a pretty central bearing on both Stripe and Arc. We'll see.

36:58

central bearing on both Stripe and Arc. We'll see. I totally agree with that general sentiment but I wonder if the meta lesson that we got from COVID,  for example, and with things like Fast Grants was: you obviously can't predict these things  in advance, but the most important thing,

37:18

in addition to specific countermeasures you  are trying to come up with in advance, is, when the crisis is happening, having competent  individuals who can synthesize and organize information, and also having new initiatives  and institutions to get the right thing done. The adaptability premium is probably  going to go way up over the next decade.

37:35

The adaptability premium is probably  going to go way up over the next decade. Yeah.

37:38

With that in mind, I know you already have  a couple of day jobs, but I feel like something similar to fast grants, when the time comes down  to it, should be there.

37:44

You'd be one of the top people you could think of, in terms of having  expertise and respect in a wide range of domains and competency as a leader.

37:54

Just keep it in the  back of your mind, maybe in the middle of your mind, given how far we are into the transition.

37:59

Well, Fast Grants was three beloved squirrels in a trench coat.

38:10

I was one of the squirrels.

38:10

It was also Tyler Cowen, who's an amazing person and a great friend, and then my wife,  who's also one of Arc's co-founders.

38:18

Fast Grants was not this giant, impressive, office that would qualify me for anything at all.

38:29

But it isn't hard to be giant, right,  to have that kind of big impact.

38:34

As an objective matter, that's true.

38:34

John and I try to be very self-aware of the limits of our expertise, which  are very proximate to us.

38:39

I'm sure if something like that was necessary, that'd be.

38:48

Look at Operation Warp Speed!

38:48

They chose a super effective domain expert, Moncef Slaoui,  to run that and it was monstrously successful, truly remarkable.

39:01

I don't know who  the Moncef Slaoui of the problem is, it would depend on the problem in question, but my  recommendation would be: "Figure out who Moncef is and go hire Moncef."

39:10

I think anybody who deemed  me the Moncef of that thing is probably mistaken.

39:21

I think you're being too humble.

39:21

Staying on  Fast Grants, now we have the retrospective of how effective the fast grants recipients were,  compared to the other grants that were given out by, let's say, the NIH or NSF.

39:32

To your knowledge,  what has been the reaction of these institutions to the discrepancy between the speed and  effectiveness of fast grants?

39:38

Have they analyzed their protocols and what happened during COVID?

39:43

Is there any retrospective there on their part?

39:49

Not to my knowledge, but I don't want that  to sound like an indictment.

39:49

Maybe they've done a lot of reflection, and I just don't know  about it.

39:54

I don't think I would know about it, even if it had happened. So, I don't know.

39:59

I don't know anything about the response at CDC or FDA or NIH or NSF or any of the relevant  organizations or their international equivalents.

40:21

So what I'm saying should be taken as not only  not critical of them, but not even as a comment to them.

40:28

I just don't know what they did.

40:28

In general, organizations are not awesome at self-reflection.

40:35

I assume as a default prior,  that some of the dynamics we discussed at the beginning of this are rooted there.

40:41

None of the  people who started those organizations are there today.

40:47

What exactly are the incentives of those  leaders?

40:47

It's not clear to me who would have the incentive to really take stock in a fully  objective and self-critical way, to figure out what was done well and what was done poorly.

41:14

I promise not to be too myopic about AI, but one more question.

41:18

Long-term, we  can't forecast.

41:18

Maybe even medium-term, we can't.

41:21

But near-term, it looks like we  might have things that look like AI agents, and they might need to trade.

41:26

What does the  financial infrastructure for AI agents look like?

41:32

That's a really interesting question.

41:32

Automated  or autonomous transactions already exist to some extent today.

41:46

Lots of services have  usage-based billing, right?

41:46

A lot of the expenses being incurred are autonomously  incurred.

41:51

No human is pushing a button when Stripe does most of what it does with cloud  computing and incurs some cost with some cloud service.

42:03

In an extremely primitive way it's  happening today.

42:03

I assume it will follow some gradient, where some of those decisions will  be made by an LLM or LLM equivalent.

42:10

There'll be an almost unnoticeably smooth continuum up to  very considerable degrees of autonomy.

42:20

It's not that we're going to wake up some month and be  like: "Oh my god, suddenly the bots have been unleashed."

42:34

This will now sound very parochial  and maybe I'm getting excessively tactical, but there'll be very interesting questions around  the legality of bots in terms of: are they treated as the responsibility of the owner?

42:53

Is there any  degree of independence granted? How does liability work?

43:00

Which rails are best suited?

43:00

What kind  of transaction velocities are we talking about here?

43:07

Because if it's a billion transactions  a second, then the properties of that system should look very different to one giant tiering  transaction every day.

43:11

If we just use the analogy of the usage-based services, those tend to incur  liabilities in tiny increments, but then to settle on a monthly basis when you pay your bill.

43:26

So  maybe these agent transactions will have that character.

43:32

There are a lot of practical applied  questions, but I think what you're saying around these autonomous transactions conceivably being an  important dimension, is very true and real and is one of the interesting ways in which the economy  might change and expand over the next decade.

43:54

It's possible that the crypto plays  some role here.

43:54

We take KYC and AML very seriously for humans: we want to know the  human that is associated with some particular financial activity.

44:13

Obviously, that's a murkier  question in the context of some AI agent.

44:13

If we, in some blurry sense, look at crypto as the part  of financial services that is de facto exempt from AML by design, then maybe that plays a role.

44:28

How long before Stripe was founded do you think a product like Stripe could have been invented? That's a good question.

44:35

Depending on what exactly you define Stripe as being, conceivably  decades earlier in that, at some level, PayPal is a kind of Stripe.

44:53

There were many  payment companies before PayPal.

44:53

You could go all the way back to cash registers, so it depends  on definitional questions.

45:02

The particular secular tailwinds that we benefited from were tied to  the rise of app stores, the on-demand economy, and maybe the startup boom post-YC and the  financial crisis; those particular tailwinds were idiosyncratic and specific to Stripe.

45:23

The  GFC was 2008 2009 and Stripe was founded in 2010, so as much as you define those as being core,  then not that much earlier.

45:30

Mostly my story of Stripe is one of market inefficiency.

45:37

I do  wonder why much of this didn't happen sooner.

45:45

I always find it really interesting when there's  cases, where it wasn't even the case that: "Well it could have been started sooner, but there was  nobody in the market."

45:50

There were many people in the market.

45:52

And they weren't just random people,  they were technology companies headquartered in San Francisco who were in the market.

45:55

Do you have  some explanation for why it didn't occur to them?

46:01

I'm hesitant to generalize too much, because  I only have maybe n equals 1 experience.

46:01

It's dangerous to over extrapolate from that.

46:09

Maybe n  equals 2 now with Arc, as a very different kind of organization, but an organization nonetheless.

46:14

Or if you include all the features of Stripe, n equals 10, 20 something.

46:18

OK, yes, depending on your definition, maybe there's some kind of samples out there.

46:22

My general view is: "For most products and most businesses, things can just be done much  better".

46:27

Moats are typically overrated.

46:27

The payments are a great example of a domain where,  on a logical basis, you would say that there are so many sources of defensibility: there's the  network effects of the account holders, the data network effects/economy of scale for fraud,  regulatory modes and barriers etc. etc.

46:50

And yet, not only does Stripe exist, but there are lots of  others.

47:00

There's a whole fintech ecosystem today, right?

47:04

It gets down to deep questions of: "What is  the binding constraint on the number of effective organizations that exist in the world?"

47:14

For any  given sector, why is it that number of companies rather than twice that number of companies and  so on?

47:18

It's about motivation, ideas and people's willingness and determination to organize  talent and so forth.

47:25

But these are kinds of more sociocultural explanations.

47:29

Hamilton Helmer is probably the leading scholar on various sources of defensibility  for businesses.

47:37

He has this niche, but very well known in the niche, book called Seven  Powers.

47:45

It tends to disaggregate the various sources of market power in this respect.

47:54

I  think that is true and important, insofar as it goes.

48:00

Nonetheless, it's kind of strange to  me that nobody had done Stripe before Stripe.

48:06

When you think about the fact that moats are  overrated and just doing the thing is underrated, what is Stripe's mode in that context?

48:12

Does that  make you think differently about Stripe's mode?

48:18

Yes, I do think that one can have organizational  and cultural moats.

48:18

Maybe this contradicts what I was just saying, or it's consistent with  it in the sense that it's a kind of cultural explanation.

48:39

In as much as we have a moat,  it's because we have a very good understanding of our domain.

48:47

We have a set of people who  actually care about solving the problems, who are continually paranoid at the prospect  that we might be forgetting something important.

48:58

So we are trying to figure out what the important  thing that could supplant Stripe's approaches is, and make sure that we build that first.

49:02

You're familiar with Conquest's laws.

49:13

There's Conquest's third law, which is that: "One  should model organizations as if they're run by a cabal of their enemies."

49:19

Presumably it's tongue  in cheek, but it's interesting to try to think: "Well, what is the kernel of truth in that and why  would it be there?"

49:27

I think what's going on is: most organizations, when they start out, are  actually trying to achieve their stated goals.

49:38

Somebody started the organization for a reason and  probably it was for the stated reason.

49:38

But then over time, that person and that set of people who  initially populated the organization depart and some set of new people come to take their place.

49:51

And there's multiple iterations of that, there's generational turnover on a continuous basis.

49:56

But  say, for the fifth generation: Why are they there and to what degree do their particular incentives  align with the originally stated goals of the organization?

50:08

There can be a lot of misalignment  there, where they're following a local path, conceivably even the leader of the organization  does it, not necessarily through any fault of their own.

50:20

They're human and they have their own  incentives and again, the original, constitutional incentives of the organization might be quite  different.

50:27

This phenomenon is a fact of life and for me these kinds of explanations are  much more useful in trying to figure out why some of these things either happen or don't.

50:44

And to your question: "In as much as Stripe has a moat, what is it?"

50:49

Others can judge to what degree  it's actually manifested and rooted in practice.

50:57

I think it is, but I'm a biased observer.

50:57

I think it would be, that people at Stripe really care about solving the problems that we say we are trying to solve.

51:06

Yeah, the point about the misalignment over  generations or over time is interesting.

51:06

Do you have examples of institutions, which have  for decades or centuries managed to keep their original, not only mission statement, but  organizational competence?

51:18

Because if you think of tech companies, even the oldest  ones have not been around that long, right?

51:28

And they're some of the biggest tech companies in  the world.

51:28

And the median age of the corporation is famously low.

51:31

What is a good example here?

51:31

Some of the explanations around the effects of shareholder capitalism suggest that it influences  the incentives of organizations and their long term fates.

51:52

Those theories have some credibility  and it’s plausible that shareholder capitalism even attenuates the duration of some of these  organizations.

52:00

I'm not saying that's definitely true, but I find the idea that it could be,  incredible.

52:05

It's unclear if that's necessarily bad if it is true, right?

52:10

In that, are we on the side  of the humans, aggregate innovation in the world, or corporations, or quad legal entities?

52:16

The  answer isn’t clear to me. It should be the third.

52:24

At the same time, if you look at Europe or places  like Denmark, because of the tax code there, a lot of organizations are either controlled or  substantially held by non-profit foundations.

52:47

For example Novo Nordisk – the GLP company,  Maersk – the shipping company, I believe also Lego.

52:54

A lot of these corporations are controlled  by foundations and usually have a lot of their stock held by them.

53:01

In many cases that has the  secondary effect, where they actually embed their mission into a legally binding constitution.

53:08

I'm  not an expert on Novo Nordisk, but I happened to get a book about it over Thanksgiving and there’s  also a book on the Danish Industrial Foundations.

53:24

It's enshrined in their constitution that they  have to make insulin broadly available and really cheap or at least that is the case in Scandinavian  countries.

53:29

So it is allowed to charge market prices elsewhere but they're legally obligated to  reinvest profits in R&D.

53:32

Is that somehow causal in the fact that they made one of the most remarkable  pharmacological discoveries of the last 20 years: GLP-1 agonists? – Plausibly.

53:53

These questions of  “Why is it that the median age of organizations and corporations is what it is?

54:06

” are definitely  interesting and I suspect the reason is somewhat dependent on the way we've chosen to  organize large corporations in the US today.

54:18

The thing you're mentioning about this firm  seems very similar to the export-led growth in Asia. Totally. The idea of tariffs.

54:24

There's one company  tasked with making the cars, so you better make the cars good.

54:27

You have no competition but  you have to invent the best car in the world.

54:31

Yes, we are all fans of Smith, Ricardo and  even they are less dogmatically attached to free trade than people today interpret them as  being.

54:46

People like Friedrich List and other, not quite contemporaries, but quasi-contemporaries  are underrated on a relative basis.

54:59

As much as you believe the kind of sociological,  cultural skill, even vague alignment in the more interpersonal sense, in as much as you think these  are important and explanatory, then you end up thinking about some of the things the US raised.

55:15

That's really interesting to hear you say that, because if you think about Stripe's  mission– it's to facilitate global trade, to make sure that some firm from India can compete  with any firm in Nigeria or whatever.

55:24

So the room for you to have this sort of learning curve  where you're less efficient than the global competition should be less, if Stripe exists,  right?

55:35

Isn't Stripe the anti-List company?

55:41

Well, it depends which version of List.

55:41

To be  clear, I'm not specifically endorsing these tariffs and trade barriers.

55:48

The history associated  with them is checkered at best.

55:48

Look, it's possible that if you have a specific sector where  you have clear goals, a credible path to actually achieving some substantial degree of success and  some conjoined propositions, then some degree of activist trade policy might be the beneficial  thing to do.

56:16

I don't think that that describes most sectors in most countries at most times. That's so interesting.

56:26

I think there's an interesting thread here in how it relates to  Stripe climate, in that you're subsidizing learning curves that East Asian countries  did for their own internal companies.

56:39

You haven't picked out a specific company that's  going to necessarily be the key to carbon sequestration.

56:49

How do you think about this?

56:49

Well, a way to unify the two points, and I'll speak about Stripe in a second, is  Say's law about demand creating supply.

56:54

In as much as Stripe aggregates more and more global  demand, it seems too self-aggrandizing to call it “The theory of Stripe", but some vague  hunch in Stripe is that this aggregation of demand can have important expansionary  effects with respect to the ensuing supply.

57:21

Stripe climate is some version of this hypothesis,  applied on a much smaller scale than Stripe itself, but still real and maybe important.

57:26

For  folks who aren't familiar, which I assume is most of your audience, the basic idea goes like this;  We observed in 2018, that everyone seems to agree, that carbon removal will be very important.

57:40

Even if we decarbonize the economy on the most optimistic timeframes, there'll still be  an accumulated stock of carbon, which will be a problem.

57:55

It sounded pretty weird, that there  were virtually no carbon removal companies in the world in 2018.

58:00

Maybe there were two or three.

58:00

No  companies had ever purchased from carbon removal companies, which were really sort of science  projects.

58:06

So we thought: "Well, somebody's got to start and it might be valuable to not  only transfer some dollars, but to confer some credibility on this sector."

58:16

Not that Stripe is  the world's most credible company, but it's better than nothing.

58:20

So we started contracting with  some of these carbon removal companies.

58:20

That went pretty well and they seemed kind of appreciative  of us and so we thought somewhat more about this.

58:30

Then, in 2021, we formed Frontier, which is an  AMC, an advanced market commitment.

58:30

That was inspired by the first AMC, which was a  pre-commitment to purchase vaccines for developing world's countries for diseases that were market  failures, where either pharma companies hadn't pursued the vaccines, or where the profits weren't  sufficient to pay for the program.

58:51

So we decided to do this for carbon removal.

58:55

We raised a billion  dollars.

58:55

Stripe was the first investor.

58:55

We're not actually investing, we're just buying, so we were  the first company to commit.

59:03

Then we were joined by Shopify and Alphabet and Meta and JP Morgan  and a bunch of other companies.

59:07

And now there's a fairly active sector of carbon removal companies.

59:16

Frontier has contracted with between 40 and 50 companies, the overwhelming majority of which  didn't exist when we started out with this.

59:24

We ran an anonymous survey back at the end of last  year, where we asked them to what degree was the existence of Frontier causal in their starting  the company in the first place.

59:37

Again, it was an anonymous survey.

59:42

I think it was 74% of the  companies that said that Frontier played a causal role in their starting the company.

59:49

So these  inducement effects can be pretty significant. Yeah, that's huge.

59:57

What are other ideas you've  come across, where an AMC would be an effective instrument of moving forward the tech? That's a good question.

1:00:01

We've been having that discussion internally.

1:00:05

It's not that we  plan on doing it ourselves necessarily, but I'm wondering: "Are there people we should share  our technology with?"

1:00:11

Not even technology per se, but share our experience and try to help along.

1:00:19

There's still a lot of stuff in the biomedical fields.

1:00:29

Patents are pretty useful insofar as  they go, but there's a lot of innovation that seems socially beneficial, that patents  don't provide a way to cover the cost of.

1:00:52

There was some excitement a few years ago about  mannose, which is a sugar.

1:00:52

There was one or maybe a few papers that suggest that maybe tumors will  selectively take up mannose rather than glucose, but they won't actually metabolize it  properly and they'll just die.

1:01:11

Maybe this could be an effective onco-treatment.

1:01:16

Mannose is like a generic sugar.

1:01:16

It's been understood for more than a century  and, importantly, you couldn't patent it.

1:01:30

So it's not clear who has the  incentive to even fund the work to test, whether or not this would actually work in  practice.

1:01:37

This is not an endorsement of mannose, but there are things of this shape, where there's  something that clearly might be very beneficial, but it's not clear how the economic structure of  the market can make it possible.

1:01:47

There are still a lot of those across the biomedical landscape.

1:01:51

There are still a lot of vaccines that could, in principle, exist that don't, like Lyme disease.

1:01:56

There was one vaccine that was withdrawn from the market over safety concerns, that I think  were misplaced, but there's still no vaccine.

1:02:09

It's not even that well understood,  right?

1:02:09

People have chronic Lyme disease.

1:02:12

We don't know if it's legit or not. Exactly.

1:02:12

But it's a good question.

1:02:12

Maybe some of your listeners will have ideas for  fields, where we sorely need an AMC.

1:02:26

I want to go back to Stripe for a second.

1:02:26

So  you're famously appreciative of craft and beauty, but you also appreciate the  power of scale and growth. And speed. Oh, interesting.

1:02:37

Is there a type of craft that is just not amenable to speed,  growth, scale?

1:02:42

If you think of a Japanese chef, he's been learning to cook rice for a  decade, and then he can move on to sushi.

1:02:52

Is that just not competitive in the modern world? Craft, scale, and speed.

1:02:52

I don't know if they are strictly necessarily intentioned in every case,  but they're definitely frequently intentioned, so yes is the short answer to that.

1:03:04

At the same  time, a lot of the most successful companies are those that are distinguished by the extent  to which they exhibit appreciation for and skill in realizing craft and beauty.

1:03:24

LVMH is  one of the largest companies in the world, and that's literally their business.

1:03:30

Tesla is  pretty good at this.

1:03:30

They're good at many things, including this.

1:03:36

Obviously, there's Apple.

1:03:36

TSMC  is not the Japanese sushi chef you mentioned, but it's the TSMC chip sushi chef in Taiwan.

1:03:47

They  have so much tacit knowledge and difficult to transfer skills.

1:03:58

It might be the case that craft  and the pursuit of it is as important as it's ever been.

1:04:10

Certainly, as Stripe has gotten larger,  we have come to greater conviction in this.

1:04:24

Part of what's interesting about these  aesthetic qualities is they're generally speaking unquantifiable.

1:04:30

I don't know  if they're intrinsically unquantifiable, maybe you could train a model to do so, but today,  they are broadly speaking unquantifiable.

1:04:33

And yet they influence people in significant ways.

1:04:42

People  very demonstrably care about aesthetics.

1:04:42

And if they're a company, they care about the aesthetic  characteristics of the products that they produce.

1:04:53

On an intuitive level, people know that that's  true.

1:04:53

But it's difficult to manage that at an organizational level, where there isn't a P&L  associated with it, and if you're screwing it up, you don't see a neat time series decline.

1:05:07

Over the 14 years of Stripe, we have, not exactly through trial and error, but by studying  cases where things worked well and less well at Stripe, what customers responded well to, and so  on, understood, that even in a domain like ours, where we are selling primarily to businesses, that  is something that's truly important.

1:05:29

Getting back to what we were discussing previously, in as much  as the sociology and "cultural" explanations of defensibility are real, the best people consider  themselves crafts people in their domain and they really, above almost all else, want to work with  the best other people.

1:05:55

It may almost be true, that even if from a customer-facing standpoint, craft  was not valued by the market, you might still want to build an organization that indexes very heavily  on this, because you just want the best people for other reasons.

1:06:16

Now, as it happens, I think  customers do, in fact, value it.

1:06:16

The evidence is broadly consistent with that.

1:06:21

It's very hard to  assemble groups of the best people, if you don't take the practice of the work super seriously.

1:06:30

What kind of beauty or craft or simplicity is more important— interface or  implementation?

1:06:36

There's famously that essay that Unix is successful because the  implementation is simple and not the interface.

1:06:44

The interface is kind of simple, but  there's a lot of edge cases that I guess Unix doesn't handle for you. But Stripe does, right?

1:06:57

Presumably, it depends what you're building.

1:06:57

For  TikTok, it's more important that their interface is simple.

1:07:02

Even if their implementation is a  mess, that's probably OK.

1:07:02

Not saying it is, I have no idea.

1:07:06

Whereas for Stripe, people are,  on some level, purchasing our architecture or purchasing their ability to do certain things  rather than some different set of things, because of what our architecture makes easy  and possible.

1:07:21

If by interface you mean the GUI, then maybe we can draw some separation there.

1:07:30

But  we don't really draw that distinction.

1:07:30

We think of the interface to Stripe as being the architecture.

1:07:35

No one else seems to agree with me, but I often think of Stripe as similar to Mathematica, where  we're selling a self-contained universe to model whatever it is of interest to you.

1:07:54

We're providing  some primitives, interfaces and tools and so forth, to enable your modeling.

1:08:05

But fundamentally,  we're helping you do something on your own terms.

1:08:13

In that sense, I don't think the architecture  and the interface are necessarily that separable.

1:08:18

That's a really interesting analogy.

1:08:18

Although, if  you think of Mathematica, the entry that that's giving you to, is just the platonic objects  of math, whereas for you guys, the entry is to Visa error codes.

1:08:30

The end object is not platonic. That's true.

1:08:30

So yes, the analogy falls down in a few respects.

1:08:42

But look, the idea of a transaction  is pretty fundamental and is roughly as old as the quadratic equation.

1:08:52

I guess the transaction's  older.

1:08:52

And Mathematica now supports all kinds of crazy, arcane stuff, to a very impressive extent.

1:09:01

If you go through the more obscure packages in Mathematica, you can definitely find things that  are much less broadly employed and understood, even less than Visa error codes.

1:09:13

But yes, these  are not the same, It's just that I find it to be an interesting source of intuition.

1:09:19

What Wolfram  has done with Mathematica is pretty amazing.

1:09:24

Another way, in which I'm curious how you think  about this, is: one way in which Mathematica maybe differs is, if they had to make a change  in Mathematica — "Big deal, somebody has to learn new syntax".

1:09:32

If you make a change — billions of  dollars of transactions don't happen.

1:09:32

How does that change the way you think about the initial architecture and the stakes? It's a good question.

1:09:46

First a point on beauty with  respect to architecture and then I'll answer that one.

1:09:54

Just as a side note, it's interesting that  API design in general doesn't get more study as a discipline and as a practice.

1:10:01

It plays or can  play a significant role in the fate of platforms.

1:10:10

Not saying it is always the determinative thing.

1:10:10

But if you get it right, there can be compounding positive benefits and the converse.

1:10:17

It's really  striking that, say with mobile app development, which was one of the most dynamic ecosystems of  the past 10 or 15 years, so many of the objects and the classes, say in iOS development, are  prefixed with NS.

1:10:32

Less so now with Swift, but for much of the iPhone's history.

1:10:39

The NS  refers to Next app, back from Next in the 90s.

1:10:47

When you get API design and architecture right,  it can be so enduring over literally multiple decades, even in the face of what are otherwise  frenzied evolutions in everything around it.

1:11:04

Unix is another example of this.

1:11:04

Yes, Unix  has tons of shortcomings, but the architecture has worked now for more than half a century.

1:11:11

We're all trying to impress upon people at Stripe the importance of multi-decadal abstractions.

1:11:21

People sometimes respond to that thinking that that's some insanely lofty, implausibly  ambitious hyperbola, but no, that's what happens, when you get this stuff right.

1:11:40

In fact, if you get it right, people building on your platform can reap  incredible benefits for a very long time.

1:11:55

To the Mathematica point, I know they take  backwards compatibility really seriously, to the point where you can run programs written 20  years ago, unchanged, in today's Mathematica.

1:11:59

That really raises the stakes in API design for sort of  obvious reasons.

1:12:08

We have that problem ourselves, where, when we think about introducing something  new, it's not just: "Does this exigently address the particular need that's motivating it today?"

1:12:19

— but: "Do we think we can stand behind this in 2044?

1:12:25

How do we think the world might evolve  around us, such that it all remains coherent?"

1:12:33

We certainly don't always get that right, but  that's, on some level, what we're trying to do.

1:12:37

Is Visa an example of this?

1:12:37

One might even say,  that one of the downsides of being able to use implementation for many decades in the future  is, even if it's self-sustainable and you have this ecosystem in equilibrium set around it, if  you can't modify it because of people's local incentives, you get stuck in this equilibrium  that's worse than it could be otherwise. I see.

1:12:58

The card networks generally, Visa and  MasterCard, are pretty good at equilibrium.

1:13:10

It's easy to judge today with the world as  it exists in 2024, but you have to look at the world as it was when they started out and the  particular problems that they were solving.

1:13:15

When you compare the financial landscape in the US or  in the Western world to those in other places, it's certainly not clear to me that the  US has gotten a bad hand, so to speak, or is somehow stuck in any meaningful way.

1:13:31

The card networks do a couple of things.

1:13:40

Originally, they were designed to replace  store credit.

1:13:40

It was a credit card originally, not a debit card, right? That was important.

1:13:49

The  availability of structured consumer credit is a pretty big deal and is beneficial, especially  for lower income people.

1:13:56

Then, with the advent of jet travel, mass market tourism and so forth,  they helped to supplant travelers checks and various worse alternatives, like carrying cash  around in your bag.

1:14:13

Then, with the internet, they were substantially involved in enabling  online transactions.

1:14:19

The fact that they got the architecture so right, that so many different  use cases were able to be addressed by their core design is really impressive.

1:14:32

The guy who designed  all this,Dee Hock, was a remarkable person.

1:14:40

People complain about interchange.

1:14:40

Lest I sound  like a defender of the card ecosystem.

1:14:40

You could look at it multiple ways, but many people would  consider Stripe to be on the wrong side of the interchange cost equation, in the sense that  we're giving away the interchange revenue to other companies.

1:15:02

So I don't think I'm structurally  biased in favor of interchange, and yet, I will say it's pretty interesting what interchange made  possible.

1:15:09

It is a distribution incentive fee, where you're paying other entities for recruiting  customers, convincing them to get a card, getting them to maintain the card and to pay it off at the  end of the month etc.

1:15:24

So you're paying for that, just the pure distribution.

1:15:29

There's a person  at the end of the flight telling you: "Hey, sign up for the United Credit Card!"

1:15:32

That's what interchange is paying for. That guy annoys me.

1:15:37

We'll get to the counterfactuals in a second.

1:15:41

So there's paying for the actual  credit issuance itself and then there's the customer support and all the ancillary things  around the dispute handling and so forth.

1:15:54

It is interesting to look at the cases  where, for whatever contingent reason, the card networks didn't rise.

1:15:58

Germany is one of  the classic ones.

1:15:58

From our vantage point, dealing with the online economy in Germany as compared  to the US is so much worse.

1:16:05

If Stripe could push a button and have really broadly adopted  cards in Germany à la the US, we would push the hell out of that button.

1:16:15

You can look at China,  which on the one hand does have Alipay, WePay, WeChat payments, that are really ubiquitous — in  that sense, they're very digitally enabled from a transactional standpoint.

1:16:32

On the other hand,  those products tend not to be as sophisticated with consumer credit.

1:16:36

So yes, the transaction fees  for transferring your money — that's super cheap, but you need to look at it on a  fully loaded basis, where: "OK, but what about the cost of actually getting the  credit to make the purchase in the first place, as a credit card would enable?"

1:16:51

And as you look  at these other counterfactuals in other places, one feels gratitude for what it is, that Dee Hock  and Visa and MasterCard and the card networks made possible.

1:17:03

I'm not saying they're perfect, that one  can't make critiques, but I'm most interested in critiques from people who've really studied the  ecosystems of other countries, because it's easy to underestimate what we got in their invention.

1:17:19

Maybe there's a Chesterton’s fence kind of thing going on here.

1:17:28

If you had to design payments  from first principles now, does it make sense that all these things you've mentioned:  taking on credit risk, the chance of fraud, dispute adjudication, should that cost 2%  or 3% of each transaction that happens in the economy?

1:17:43

What would payments look like if  you had to design that from first principles?

1:17:49

We're seeing a live version of this  experiment play out for the first time in many years in a number of countries  today, where central banks are becoming more active in designing national payment schemes.

1:17:59

PIX in Brazil launched in late 2020.

1:17:59

I'm sure you've heard of UPI.

1:18:10

UPI was the instigator in  this process.

1:18:10

It's the central bank payment system in India.

1:18:17

And it was tied up with AadHaar and  their national identity system and so on.

1:18:17

That inspired a lot of central bankers in other  countries to go and build their own UPIs.

1:18:25

So PICS in Brazil launched in 2020 and now a  significant majority of all Brazilian adults are weekly active users of PICS.

1:18:31

Again, even  though it launched in 2020.

1:18:31

So it just had this incredibly rapid adoption curve.

1:18:37

You have Swish  in Sweden, There are examples across East Asia, Japan, Thailand, Switzerland.

1:18:46

Central bank  after central bank is deciding: "Hey, we should have our version of this."

1:18:52

This is a kind  of reinvention of the payment system from scratch.

1:18:59

For some weird reasons hard to understand,  once you layer in the customer support, consumer protection, fraud prevention,  anti-money laundering controls and the credit, things seem to asymptote at around 2% or 3%.

1:19:14

It's important to also note that beyond just covering the costs, much of it ends up  getting remitted to consumers in the form of rewards, not in every country, but in many  countries.

1:19:28

If you look at the public reports from various banks in the US, their interchange  revenue, where they're getting these delicious fees on every transaction, as you put it, a  lot of that is going straight back out the door to the consumers.

1:19:48

So it's not clear how  exactly one should think about economics.

1:19:48

If it's going back to the consumer, should  you include that as a transaction tax or is it just like a weird circular relationship?

1:19:56

I've not seen any evidence to suggest that the 2% or thereabouts is massively inefficient in the  scheme of things.

1:20:04

I'm not saying it's the optimal level— maybe 1% would be better, but within some  range of 1% to 3%, it's probably reasonable.

1:20:21

As we think about these ad valorem fees and  figures, the place where there's even more change at the moment that we find ourselves thinking more  about is the changing structure of global tax.

1:20:46

There's been a reasonable amount of innovation in  the tax domain over the last century: income taxes got pretty high, then we added value taxes, and so  on.

1:20:54

The new thing, at least in the online context, is jurisdictions remitting or imposing  sales taxes on businesses that don't have any "locus" in the jurisdiction in question.

1:21:12

So if you're a podcaster in the Bay Area, hypothetically "Dwarkesh merch store" will have  to pay the town of Uppsala in Sweden, which will have a special tax on baseball caps.

1:21:29

And you will  need to know about that particular tax on baseball caps.

1:21:36

And for any baseball caps that you are  selling to the Uppsalians, you'll have to collect that amount from the buyer, report to Uppsala, and  then eventually figure out how you're going to get that money to Uppsala.

1:21:48

Obviously, it's this  combinatorial problem of buyer jurisdictions and product types, and then all the different  jurisdictions that you have to remit the money to.

1:22:01

As to those amounts, we're not talking three  basis points — the taxes in question are often 5% or 10%, so it's not trivial.

1:22:08

As I think about  the funds flows on the internet and how all that's evolving and unfolding, I think changes in  tax law are actually a much bigger deal than anything about the transactional economics.

1:22:23

By the way, it's not the Dwarkesh podcast, it's Lunar Society Podcast LLC registered  on Stripe Atlas.

1:22:26

Any merchandise I sell in the future, Stripe will take care of that. Yes, OK.

1:22:32

If anyone has Stripe complaints.

1:22:36

No, it's great, It has been super useful,  honestly.

1:22:36

It would have been much more difficult to get business operations going.

1:22:40

Sorry, I know you're supposed to be interviewing me, but did Stripe play any, even on the margins,  counterfactual role in you charging for anything?

1:22:51

This is the thing we're always interested in.

1:22:51

When  we talk about growing the GDP of the internet, it's not like: "Get the existing GDP onto our  rails", — it's sort of: "Where on the margin can we cause there to be economic activity  that isn't already occurring?"

1:22:59

So yeah, you did, in fact, start the podcast before  incorporating, but were we causal in any fashion in the merch or anything of that nature?

1:23:13

To the extent that Substack would not be a convenient place to get payments from to begin  with, that's definitely a thing. And also...

1:23:27

You wouldn't charge for the newsletter  if Substack hadn't made it super easy? Yeah.

1:23:30

And also, if I do an ad, I wouldn't  even know how to begin with getting the money, if I didn't already have an LLC through  Stripe with the dissociative bank account, that I'm going to get the money through.

1:23:39

So yeah,  probably counterfactually responsible for a lot of the monetization. That's cool. Appreciate it.

1:23:49

What are some unexpected  complements to payment processing you see in the future?

1:23:55

All this stuff: Atlas,  identity fraud, detection — in retrospect, it might not have been obvious back then there  was a good complement, but now it does seem that way.

1:24:08

What would be like this in five, 10 years?

1:24:08

Honestly, our problem ends up being that more things then we could possibly pursue, look like  complements.

1:24:20

In that every business almost by definition has revenue we obviously want to help  them generate, accept, manage and orchestrate everything pertaining to that revenue.

1:24:35

But  once you're in that flow and you go through the steps of running a business, a lot else looks  relevant and somehow connects quite directly.

1:24:54

When Stripe started out, it definitely wasn't  cool.

1:24:54

It was the opposite, it was just a couple of us and we thought that we could make this  superior payments API.

1:25:02

For the vast majority of its history, Stripe has attracted people  who are drawn to unglamorous infrastructure challenges and problems.

1:25:17

We're not a company  that specializes in making beautiful cars— we make roads.

1:25:27

I bring all of that up, because  it's relevant to this complement question, where in our discussions internally, a lot of  it, probably the significant majority of it, is still about: "OK, where are there practical  shortcomings and limitations in even our core bread and butter?"

1:25:49

Payment processing might be a  slightly too limited term to use for us.

1:25:49

It's more about global programmable money orchestration,  which, yes, is consumer to business payments, the sort that we were just discussing in, say,  the context of your Substack.

1:26:05

But it's also business to business payments, payments where  there's credit or lending involved.

1:26:07

It's also how you hold money, how you convert money between  different currencies.

1:26:15

It's how you represent money that's held by different legal entities and how  we make it possible for even individuals or small businesses to act as micro multinationals.

1:26:27

But those problems that we just skimmed over, even though they all directly pertain to the  movement of money, they're not small.

1:26:37

If we could just solve those really effectively, then Stripe  will be a very consequential organization and force in the world.

1:26:53

The counterfactual importance  of building some of this stuff, as we go to newer markets that are, on a relative basis, more poorly  served, is increasing rather than shrinking.

1:26:59

In the US, there were payments companies before  Stripe and maybe, if Stripe had never done its thing, eventually you'd have found some way to  monetize a newsletter or something like that.

1:27:14

But if you're in Albania, the set of options  available to you is far more restricted.

1:27:14

The marginal impact as we expand globally increases  quite a bit.

1:27:27

Even though we are interested in and do pursue some of these direct adjacencies  today, the core problem of global money orchestration remains really big and unsolved.

1:27:43

Does that look like being a better interface for all these complexities and glossing them over  under the seven lines of code?

1:27:51

Or does that look like replacing the rails and the infrastructure  to make all this more efficient and effective? The former.

1:28:02

It's not that useful to build  financial ecosystems, that are self-contained.

1:28:09

A financial island is not that helpful.

1:28:09

It's  much more valuable to build a financial, this is mixing metaphors, but a financial "air  network".

1:28:17

We would much prefer that Stripe plugged into every existing system, rail, domestic  organization, rather than that we tried to come along and supplant them.

1:28:39

And this has  been Stripe's strategy very deliberately from the beginning, where there were lots  of companies, when Stripe started out, that were trying to do their own thing and  go their own way, whereas our belief was: you get these classic Metcalfe's law stuff —  by enhancing the capabilities of an existing ecosystem, you create quite a bit more value.

1:28:58

OK, let's go back to Stripe.

1:28:58

Is Stripe a writing culture for the benefit  of the writer or the reader? It can be both.

1:29:08

But which one is the more so?

1:29:12

There are really considerable benefits on both  sides, because for the reader, it's not just that it's maybe more efficient to communicate  stuff through text, though in many cases it is, but also there's intertemporal benefit, where  future readers can try to understand the through line and the thought process that led us to  this point.

1:29:28

And that's very considerable.

1:29:34

But it's also true that I and lots of people  write things in order to organize one's own thoughts.

1:29:40

If that ability was taken away from  me, I'd be meaningfully less effective.

1:29:40

How exactly those bounce out is hard to say.

1:29:48

They're not actually separable. That's my answer.

1:29:58

Literate cultures are just a  different thing.

1:29:58

I don't mean literate in some kind of faux intellectual way,  textual cultures is a better term here.

1:30:16

Bruno Latour spoke about how he thinks  the printing revolution, like Gutenberg's, partially caused the scientific revolution  by making knowledge more rigid.

1:30:27

Before, if some observation didn't match some claim,  you could always shrug and be like: "Well, the person who transcribed that thing made  a mistake."

1:30:39

So by making things more rigid, it's easier to break them.

1:30:44

Then you can notice  discrepancies between the theory and the reality.

1:30:52

There's some version of that organizationally,  and I'm not drawing a precise parallel, but there are analogous dynamics, where the  nature of oral cultures and textual cultures are just quite different.

1:31:03

The kinds of collaboration  that are possible, kinds of consistency, that can be achieved, are just fundamentally different.

1:31:14

Is the front or rear wheel of the bicycle more valuable?

1:31:25

Theoretically, you can be a unicycle,  but as a practical matter, you do just need both.

1:31:31

I know I said no more AI questions, but on this  particular point, it seems very legitimate to me, that you might expect firms, that have a lot  of writing, to be the first to experience the productivity gains of AI, because in other  cases there's all this context that the model doesn't have readily available.

1:31:45

I don't  know if that's something you anticipate. That's probably true. Yeah, I don't  know.

1:31:49

If the model is really good, maybe it's able to pick stuff up quickly.

1:31:53

Most organizations are not recording all of their meetings for a variety of reasons, and  if they're not, then there is this question of: "What is the corpus?

1:32:03

How do you get up to  speed?"

1:32:03

So yeah, my guess is that will be true.

1:32:08

Tell me about the internal LLM you built.

1:32:08

Oh, we didn't build an internal LLM, we built an internal LLM tool for making it very easy for  people to integrate LLMs into production services, but also into their regular workflows as humans.

1:32:25

We added the ability to work directly with the LLM, as a standard chat agent, as lots of people  did, but then also to integrate that with some of our tools for querying and accessing data, most  interestingly, we added sharing prompts across different people, so that somebody might  discover these prompts.

1:32:50

One of my favorite examples is: somebody put together a prompt for  optimizing SQL queries.

1:32:54

It doesn't always work, but sometimes it does.

1:33:04

It's very cheap to ask us:  "Got any ideas for optimizing the SQL query?"

1:33:04

And sometimes it will come up with some good stuff.

1:33:11

So the collaborative abilities there have proven surprisingly high return.

1:33:21

And then having, lots  of organizations have this — we're not claiming that it's very novel — but having a central  bus through which to route all access to these LLMs, in such way, that we can experiment  with different models and have some degree of observability into the respective performance  trends and the usage of different cases.

1:33:41

We have found building a fairly significant amount of  production infrastructure around LLMs to be valuable.

1:33:58

And now, given the proliferation of LLMs  themselves, with all of the obvious contenders, this is proving quite valuable, because we're  able to try to figure out for different use cases which models: self-optimized or  who knows which, are most effective.

1:34:15

I don't know what the total number of invocations  is, but I think we're making millions of invocations per day now.

1:34:21

There are dozens of  dozens of actual production use cases across Stripe.

1:34:27

The financial services ecosystem is, in  some way, a giant analog to digital exercise, because humans, intentions, identities are analog  — all these things have some degree of uncertainty around them and some noise.

1:34:50

But then transactions  are digital, right?

1:34:50

And we often find in these analog to digital conversions, that LLMs can  be a surprisingly interesting augmenting tool.

1:35:04

On that point about the flexibility and the  edge cases in the way humans interact with these systems: in some sense, Stripe is a really  high stakes bug bounty program, right?

1:35:12

If somebody hacks it, if there's reliability issues, not just  because of a hack, but because you deployed the wrong way, not only the financial services—  obviously, money's in play— but a significant percentage of rural GDP would grind to a halt, at  least while it's down.

1:35:32

How do you deal with that kind of responsibility?

1:35:39

How do you keep the uptime  and keep the reliability while deploying fast?

1:35:45

This is one of the things we've spent the most  time on.

1:35:45

Back to this point about wanting to be the place with the best people and the value of  focusing on craft, so that you can have the best people.

1:35:58

In the context of software development,  two things developers hate: slow development cycles: it'll ship in the next release in a month  and that kind of thinking.

1:36:10

Developers also hate being paged at 2 AM for incidents.

1:36:17

So, given  the criticality of the businesses that we serve, which is, in rough terms, 1% of the global economy  — it's not totally clear how to measure this, because GDP is defined as final goods and Stripe  is not only selling final goods, so, in theory, there could be a bit of double counting.

1:36:46

But  Stripe is mostly selling final goods.

1:36:46

We're not used, by and large, for giant supply chain  shipments.

1:36:50

Maybe there's a mismeasurement of 10% or 20% or something.

1:37:00

But long story short,  I think it works out to about 1% of global GDP.

1:37:05

It's about a trillion dollars a year.

1:37:05

As you say,  that then makes us really terrified of outages.

1:37:11

And so we work so hard to enable fast iteration  and development cycles without having outages, and to put some numbers on it: we deploy  production services that are in the core charge flow around 1,000 times a day.

1:37:25

Most of  these services are automatically deployed, so when anybody makes any production-ready change, it  just goes into production.

1:37:33

It's meticulously and carefully orchestrated: first is just running some  small sliver of traffic and then incrementally more traffic until it's everything.

1:37:46

So about  1,000 deploys per day at roughly or somewhat in excess of five-and-a-half-nines — 99.

1:37:54

9995%  reliability — which works out to about two, two and a half minutes of unavailability per year.

1:38:05

It's not that we have, obviously, two and a half continuous minutes of unavailability, but that's  what it approximates to, even though it tends to happen as background radiation throughout the  year.

1:38:16

Getting to that point takes a huge amount of investment.

1:38:24

Then there are security properties  that are less readily measured, but analogous to those figures.

1:38:31

Silicon Valley doesn't tend to...

1:38:31

I'm perhaps now being unfair in attributing things to Silicon Valley — a lot of the tech industry  doesn't place a lot of value on process and operational excellence.

1:38:46

We culturally value the  spontaneous, the creative, the iconoclastic, the path-breaking.

1:38:55

Building mechanisms that can  enable the very reliable provision of important services at scale, and removing the sources of  variability, that can really cause a bad day for a very large number of people — I don't think  these things get quite as much cultural credit.

1:39:36

None of this sounds like rocket science,  but defining what it is, that we care about, and then building automated measuring systems to  measure to what degree it's happening in practice, to then try to figure out the cases where  we're not living up to that, and determine what is the reason, then to actually intervene and  improve the system, so that that's not happening,

1:39:56

then importantly, to build secondary controls,  that detect instances of deviation long before they cause a production problem, but where  we understand the behavior of the system in sufficient detail, so that we can instrument it in  some upstream way — most of what I said there was well understood by production engineers in 1930s. So again, I'm not claiming that it's any kind of

1:40:18

So again, I'm not claiming that it's any kind of radical breakthrough, but we have found that the  adoption of these practices in really tenacious multi-year form yields really high returns.

1:40:29

There  may be other organizations that both ship at that rate and maintain that developer velocity at this  combination of scale and reliability and security, but I don't think there are that many.

1:40:52

It's a real testament to the remarkable folks at Stripe who made it happen.

1:40:58

Last point, the fact that you have this huge internal tooling and testing is...

1:41:04

Once you get the AI engineers, they can push the commits and you have the infrastructure  set up, so that it can be readily evaluated. Yeah.

1:41:15

Across the board, so much comes back to what  has to be true for us to be able to build and to take seriously this goal of building the best  software.

1:41:27

It's easy to say that as some lofty, vague, hand wavy aspirational statement.

1:41:35

But if  you take that seriously as a goal — you think about what you would have to measure,  if you were actually going to pursue it in earnest?

1:41:46

— part are the characteristics of  organizations that do produce it.

1:41:46

You get down to: "Well, customers have to really like your  stuff.

1:41:52

OK, how can we measure that?

1:41:52

And how can we systematize the process of making  sure that there aren't repressions there?"

1:42:02

We have this concept of “experience journeys”,  which are pathways through Stripe, that we really care about and that are always implemented at a  really high quality level.

1:42:07

And it has to be true that developers can iterate over them very quickly  — we just spoke about how to make that happen etc.

1:42:21

A theme through everything we've talked about  is taking the goal seriously.

1:42:21

And I feel like a lot of what we do at Stripe is — again,  I disclaim any genius in it — just the very earnest, repeated, serious, and long term  application of taking the goal seriously.

1:42:41

A few more Stripe questions.

1:42:41

One percent of  global GDP is such a staggering number.

1:42:41

When you think about where further growth for Stripe  comes from, does it come from the internet economy expanding?

1:42:54

Or does it come from Stripe becoming  a larger share of the internet economy?

1:42:54

And to the extent that Stripe is growing faster than the  internet, if we consider that to be the beta in your case, where is that alpha coming from? That's a good question.

1:43:04

The customers that Stripe serves in aggregate are outgrowing the  internet economy as a whole.

1:43:13

At some point, those have to converge for obvious mathematical  reasons.

1:43:23

But we're 14 years in and they haven't converged yet.

1:43:28

There's a lot of headroom there.

1:43:28

Say Stripe is handling around a trillion dollars a year.

1:43:33

When Stripe started out, the global economy  was sixty to seventy trillion-ish.

1:43:33

The global economy is now around a hundred trillion.

1:43:39

We still  have quite a bit of headroom before the amount of activity that is coming out to Stripe is really  butting up against the ceiling of global economic growth.

1:43:52

And of course, there's no ceiling on  global economic growth for all sorts of reasons.

1:44:00

It could be vastly higher than it is.

1:44:00

And I don't  even mean new technologies or AIs, but just all the basic per-capita math you can do around.

1:44:07

What  if everybody had an income on par with the US?

1:44:15

One of the reasons I am so interested in working  on Stripe is: it's the old line, the Lucas line, about how when you start thinking about  differential rates of development in countries, it's hard to think about anything else.

1:44:27

Why  does Brazil have the particular income and GDP level that it does?

1:44:31

Why does Poland have  the level that it does?

1:44:31

Why did Ireland have the trajectory that it did, where it went from  being the sick man of Europe to now one of the wealthiest countries there?

1:44:41

I feel like Stripe is  some applied version of this question in practice, where you're building software products, but in  some sense connected to or touching upon these questions of: Why aren't there more companies?

1:44:53

What determines the growth rate of a company?

1:45:03

Why is it that when you start the merch store,  why does it have X level of buyers rather than 2X?

1:45:12

I think those remain fruitful questions.

1:45:12

We haven't optimized the meta system of business to any particularly great extent.

1:45:26

For the vast  majority of time, businesses have been offline, inefficient, analog.

1:45:32

It's really only  over the last one to two decades that a significant share of this has been meaningfully  digitized.

1:45:43

And the prospects for optimizations there are still significantly underexplored.

1:45:50

We find incredibly basic things, like 'just extending capital to businesses'.

1:45:58

The reason we  do that is not to generate profit from the loans, but because we find that the businesses,  whom we extend the capital for, then just grow faster on a persistent subsequent basis.

1:46:08

Or, trying to figure out, how does a business decide which countries it sells in?

1:46:18

And you'll  find for even the smallest business through to some of the largest businesses in the world,  that these are very ad hoc and not deeply thought through questions.

1:46:31

Like: "Why don't you  sell in Mexico or in Brazil or whatever?

1:46:31

— Well, it seemed complicated, and so we  didn't quite get around to it."

1:46:41

To your question about: where does the  growth come from?

1:46:41

There's still an awful lot of low-hanging fruit in just asking  some of these incredibly basic questions.

1:46:52

So, when we think about the way in which  Stripe will continue to grow in the future, in some sense, it will obviously involve a  lot of big businesses.

1:46:58

You're now processing a significant amount of Amazon volume, there are  these other businesses you're doing deals with.

1:47:08

First, tell me how you think.

1:47:08

It makes sense  how an exponentially growing startup would contribute to exponential growth for Stripe.

1:47:12

How  does Stripe keep growing at the same trajectory, when it's these existing big businesses  that you're partnering with?

1:47:18

And second, the case for why these startups matter is so  compelling, right?

1:47:24

A new thing is coming into this world, and we should really support it and  make sure it happens.

1:47:28

Why is it compelling that Amazon can fulfill orders more efficiently?

1:47:32

Those are very good questions.

1:47:32

On the first one — you're right.

1:47:45

Stripe is doomed to eventually  grow at the rate of the economy, there is only a question of how long it takes to get there. Right.

1:48:02

The good news is that it can be a very long  time, because there is, as we just discussed, so much low hanging fruit around different  improvements that are possible.

1:48:08

So I think it'll be many decades before that happens.

1:48:17

But it's true: that will eventually occur.

1:48:24

On the second question: "It's obviously  virtuous or compelling or exciting to foster all these nascent startups and to be an  anti-incumbency force.

1:48:33

But what's the case for supporting established businesses?"

1:48:39

People  misunderstand that for a small business, typically, at least in the cases where we  denote them startups, there's usually an embedded innovation.

1:48:50

And this innovation is all  that the company is.

1:48:50

They have a new idea, and they're going to do something better or different  etc.

1:48:55

Generally speaking, we like innovation and so we have positive sentiments towards that  startup.

1:48:59

But there's a lot of innovation that comes from large established businesses.

1:49:04

That's  not all they do, they are also just running the existing thing.

1:49:09

So maybe it's a smaller share,  but the aggregate fraction of innovation that comes from established businesses is really large.

1:49:16

We have to be cognizant of the cognitive bias, of the startups being more conspicuous.

1:49:24

On a  relative basis, the improvements in turbine, fab or insulation technology come largely from  established businesses.

1:49:34

To choose any sector of the economy, a significant fraction of the  important inventions that occurred over the last 10 or 20 years will have come from the incumbents.

1:49:49

As a general class, and Tyler wrote a book on this, big business is underrated.

1:49:58

If you look at  the survey data, people tend to have very positive sentiments not only towards startups, but towards  small business as a class.

1:50:06

Even though they have negative sentiments or relatively negative  sentiments towards big business, it is not that bad on an absolute basis, but not as favorable.

1:50:16

It's true that established businesses tend to pay better, tend to be more efficient, more  of the innovation in our economy comes from them and they produce a lot of consumer surplus.

1:50:27

The specific case for Stripe working with them is: typically they're coming to us not because they  want to take the thing that they're already doing and go through all the work of transposing  to Stripe, but because either they want to do a new thing, that they're not doing today  — so it is associated with some new business line or innovation or invention.

1:50:52

Or they've  spotted the opportunity to produce a new product and want to meaningfully change how they  provide an existing one in a fashion that, again, yields consumer surplus.

1:51:07

That sounds very  abstract and theoretical, but in practice, it tends to mean they want to take what they're  selling in this market and sell it in many more markets.

1:51:16

Or they've realized that they're  selling it in this modality, and they should sell it in other more convenient ways, like on  mobile or something.

1:51:20

In each of those cases, if it's successful, if people buy it in significant  numbers, we're getting this decentralized signal from the economy, that there's now something of  value being provided, that wasn't heretofore.

1:51:41

As I take stock of the businesses, the enterprises  that are in the process of migrating to Stripe or that did so over the last year, whether it's the  large retailers, global manufacturing firms or shipping companies, it typically has one of those  two patterns.

1:51:57

New product or current product sold to people who weren't buying it before. Yeah.

1:52:06

If you think about the big trends in society that are needed to solve our big problems,  like Moore's Law or the cost of solar, you have marginal improvements over many decades. Yes.

1:52:20

Big tech or big companies are just able to  invest a lot of money into doing the R&D.

1:52:23

Relentless iterative improvement,  yes. It's underrated.

1:52:26

Can I ask about John for a second? Sure.

1:52:29

You guys recently published Poor  Charlie's Almanac and subsequently, Charlie Munger has passed away.

1:52:32

Did Munger  ever comment on your relationship and if or whether it reminded him of his and Buffett's?

1:52:39

Not to me, but he knew John better.

1:52:39

So it's possible that he did to John. Yeah, I don't know.

1:52:47

What have you learned about marriage from John?

1:52:56

This co-equal, intense, lengthy partnership — the  closest thing to that you have is marriage, right?

1:53:03

Well, I'm relatively new to the practice of  marriage.

1:53:03

So maybe in a decade I'll be able to extract the generalizable commonalities.

1:53:09

The  general thing I'd say is: working with people you're close to is underrated.

1:53:20

I'm doing Arc with  Patrick Su and Silvana.

1:53:20

Fast Grants was with Tyler and Silvana.

1:53:32

Stripe is obviously with John.

1:53:32

I  should mention, John was also instrumentally involved in Arc's formation.

1:53:40

It would not have  happened without John.

1:53:40

I could give more examples, but I feel like all the ventures of any  significance in my life, have not only been with others, but been with other people that I'm very  close to.

1:53:55

I had and would like to have an enduring relationship that outlives these ventures.

1:54:02

Sometimes one hears the advice that you shouldn't work with friends, maybe you shouldn't work with  your partner or something like that.

1:54:08

All these things are idiosyncratic and there are instances  of every possible permutation.

1:54:15

But for me, it's been a really rewarding experience.

1:54:22

And I think John and I can work together for...

1:54:29

You never know life, but I think we'll  probably work together for decades.

1:54:29

For us, it's been both an important source of meaning  and, again, fulfillment, but also there's a real complementarity.

1:54:47

Stripe would be a less  effective company without either of us.

1:54:47

And I'm just meaning from a bandwidth standpoint, but  I think we both bring different things to bear.

1:54:59

Patrick, I think that's a great place to leave  it.

1:54:59

Thank you so much for coming on the podcast. Thank you. Hey, everybody!

1:55:02

I hope you enjoyed that episode.

1:55:07

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1:55:07

Send it to people you think might enjoy it.

1:55:12

Put it on Twitter, your  group chats, etc.

1:55:12

It just splits the world.

1:55:17

Appreciate your listening. I'll see you next time. Cheers.