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AI Is Coming For These 3 Industries In 2026 (a16z Big Ideas)

AI Is Coming For These 3 Industries In 2026 (a16z Big Ideas)

16 segments available

AI is reshaping the foundations of industry, finance, and enterprise software. In part two of Big Ideas 2026, we explore three shifts redefining how systems scale. Ryan McEntush breaks down the rise of the electro-industrial stack and the challenge of building a U.S. ecosystem to power modern industry. Angela Strange explains why financial services and insurance are reaching a tipping point, where replacing legacy systems unlocks unified data, parallel workflows, and major margin gains. Sarah Wang looks ahead to a dynamic agent layer that overtakes traditional systems of record. Together, these ideas point to a clear shift: advantage moves from software to systems, from fragmented plumbing to AI-native platforms, and from static records to agent-driven execution. Timestamps: 0:00 Big Ideas 2026 0:36 The Electro-Industrial Stack (Ryan McEntush) 0:56 America vs. China: Industrial Ecosystems 2:12 Blending Talent and Building Prestige 3:56 The Importance of Supply Chains 4:22 A Turning Point in Financial Services (Angela Strange) 4:49 AI-Native Infrastructure and System Unification 5:35 Expanding Categories and 10x Winners 6:24 Why Now? The Drivers of Change 7:25 Opportunities for Early Adopters 8:06 The Power of Unified Data 8:55 Call to Founders: The Opportunity in 2026 9:23 The Dynamic Agent Layer (Sarah Wang) 9:50 From Systems of Record to Dynamic Agents 10:28 The ITSM Example and Agent Layer Value 11:19 The Race for Better Solutions Resource: Follow Ryan on X: https://twitter.com/rmcentush Follow Angela on X: https://twitter.com/astrange Follow Sarah Wang on X: https://twitter.com/sarahdingwang Read more all of our 2026 Big Ideas Part 1: https://a16z.com/newsletter/big-ideas-2026-part-1 Part 2: https://a16z.com/newsletter/big-ideas-2026-part-2 Part 3: https://a16z.com/newsletter/big-ideas-2026-part-3 Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://twitter.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see [a16z.com/disclosures](http://a16z.com/disclosures).

Segments Timeline

1
0:00 - 0:37
0:37 duration103 words

Big Ideas 2026

"Welcome to part two of our 2026 Big Ideas. Ryan Macintosh explores the rise of what he calls the electro-industrial stack, a new foundation for how we build and power America's industrial future. Ange..."

2
0:37 - 0:57
0:19 duration64 words

The Electro-Industrial Stack (Ryan McEntush)

"investing partner on the American Dynamism team. My big idea for 2026 is that the electro-industrial stack will move the world. The next industrial evolution won't just happen in factories, but inside..."

3
0:57 - 2:13
1:16 duration281 words

America vs. China: Industrial Ecosystems

"common uh tropes people report on. People talk about China's so far ahead uh we can't catch up. And actually, you know, you go back a couple years ago and people were saying, you know, China's very fa..."

4
2:13 - 3:57
1:43 duration375 words

Blending Talent and Building Prestige

"stack or the core components that feed into these technologies in the United States uh you need to blend Silicon Valley software talent and culture uh with industrial veterans. Even companies like Spa..."

5
3:57 - 4:22
0:25 duration73 words

The Importance of Supply Chains

"artificial intelligence get stronger and they start having you know more of a presence in in automation and industrial military owning these supply chains is going to become even more important. And I..."

6
4:22 - 4:50
0:28 duration65 words

A Turning Point in Financial Services (Angela Strange)

"I'm Angela Strange, a general partner on the AI applications fund. And my big idea for 2026 is there will be a dramatic turning point coming to financial services and insurance where finally the risk ..."

7
4:50 - 5:35
0:44 duration120 words

AI-Native Infrastructure and System Unification

"next generation of infrastructure doesn't just add AI. They unify the data from legacy cores, from external systems, from unstructured data into a new system of record, enabling FIS not only to scale,..."

8
5:35 - 6:26
0:50 duration147 words

Expanding Categories and 10x Winners

"instance, customer data from onboarding, KYC, KYB, transaction monitoring, even how those customers behave with your customer service team could all sit into a single risk platform. brings together fr..."

9
6:26 - 7:25
0:59 duration169 words

Why Now? The Drivers of Change

"Primarily three reasons. One, we have to remember that many of these companies still live on mainframes, decades old mainframes, and their systems were already on the verge of breaking with the scale...."

10
7:25 - 8:07
0:41 duration129 words

Opportunities for Early Adopters

"see a ton of opportunity here and potentially a dramatic reordering of the winners and losers of incumbent companies based on who become the early adopters of some of these new platforms. And we're al..."

11
8:07 - 8:56
0:49 duration117 words

The Power of Unified Data

"investor that I get so excited about infrastructure is that it's beautiful infrastructure that enables beautiful consumer experiences and beautiful business experiences. For instance, why does your ba..."

12
8:56 - 9:23
0:27 duration65 words

Call to Founders: The Opportunity in 2026

"going to see a dramatic acceleration for any company that has built a new AI first platform that sells into this large industry. But the opportunity is massive. So if you are a founder who deeply unde..."

13
9:23 - 9:51
0:27 duration85 words

The Dynamic Agent Layer (Sarah Wang)

"I'm Sarah Wang, general partner on A16Z Growth, and my big idea for 2026 is that systems of record start to lose their edge. A passive system of record layer stops making sense when agents can indepen..."

14
9:51 - 10:29
0:37 duration109 words

From Systems of Record to Dynamic Agents

"losing privacy lightly at all. I used to work at a firm that almost exclusively invested in ERPs and other systems of record because of the stickiness of the data gravity. There was a wave of SAS 2.0 ..."

15
10:29 - 11:19
0:50 duration153 words

The ITSM Example and Agent Layer Value

"IT service management. This has traditionally been the domain of powerhouse company Service Now. I chatted with a head of IT recently who told me for the first time in his two decade long career he be..."

16
11:19 - 12:23
1:04 duration207 words

The Race for Better Solutions

"there's a couple of valuable layers in this new paradigm. Of course, there's the foundation model layer. We believe that stays valuable. Um, but it's really the emerging agent layer that sits as close..."