
47 segments available
The Mitochondria Scientist Dr Martin Picard reveals why stress is secretly burning 60% of your daily energy, the science behind reversing gray hair, and why your mitochondria - not your genes - determine how fast you age! Dr Martin Picard is a Professor of Behavioral Medicine and Director of the Mitochondrial Psychobiology Group, who specialises in how stress, emotions and lived experiences affect your mitochondria. He recently published the world's first map of mitochondria in the human brain and is also the author of the upcoming book, ‘Energy’. He explains: ◼️ Why depression is really an energy problem, not just in your head ◼️ Why eating more food won't give you more energy, and what actually will ◼️ How training for a marathon can double the mitochondria in your muscles ◼️ Why people with a strong sense of purpose have more powerful mitochondria ◼️ Why cancer cells abandon their mitochondria, and what it means for treating them 00:00 Intro 03:36 Why Everyone Is Talking About Energy Right Now 04:35 Why I Dedicated My Life to Studying Mitochondria 05:51 The Fascination With Mitochondria—and What a PhD in Them Really Means 08:46 How Understanding Energy Can Help You Feel Better Every Day 10:03 Where You Should Start If You Want More Energy 14:26 Why Mitochondria Are the Foundation of Your Health 16:42 How Mitochondria Made Complex Human Life Possible 19:04 What Insulin Resistance Reveals About Your Body's Energy System 20:36 How Mitochondria Influence Cancer Risk 23:17 What Really Causes the Warburg Effect? 24:43 Why Diabetes Raises Your Risk of Cancer 26:10 The Real Reason Smoking Causes Cancer 31:04 Why Hair Turns Gray—and Whether It Can Be Reversed 39:57 What Cortisol Is Really Doing to Your Cells 42:47 Does a More Resilient Mind Save Cellular Energy? 45:20 Acute vs. Chronic Stress: Why the Difference Matters 45:54 Understanding Resistance—and Why It Drains Your Energy 48:18 What Happens Inside Your Body When the First Gray Hair Appears? 51:43 The Real Secret to Healthy Aging 53:37 How to Make Your Body More Energy Efficient 55:34 How Food Changes the Way Your Cells Produce Energy 01:01:02 What the Energy Crisis in Your Cells Means for Alzheimer's Disease 01:05:32 Is Dementia Really "Type 3 Diabetes"? 01:12:07 Why Some Communities Avoid Dementia—and What This Means for Alzheimer's Risk 01:13:54 Ads 01:15:56 How to Eat for Optimal Energy and Health 01:17:27 Why We Overeat Even When We're Not Hungry 01:20:46 Is Breakfast Really the Most Important Meal of the Day? 01:22:43 How to Stop Scattered Energy From Running Your Life 01:30:58 How High Performers Filter Signal From Noise 01:39:52 How Energy Resistance Shows Up in Parenting 01:41:54 Why Meaningful Goals Become Magnets for Your Energy 01:42:35 Does Having a Purpose Improve Mitochondrial Function? 01:46:22 What Being Judged Does to Your Body's Energy System 01:51:07 Why Stress Causes Visceral Fat Gain 01:51:30 What Happens When Chronic Stress Turns Into Disease? 01:53:03 How to Reduce GDF-15—and Why It Matters 01:56:28 Can Supplements Actually Improve Mitochondrial Health? 02:00:23 How to Trust the Wisdom of Your Body 02:02:22 Ads 02:03:26 Can Red Light Therapy Really Support Your Mitochondria? 02:05:12 What You Need to Know Before Trying Red Light Therapy 02:10:33 How to Listen to What Your Energy Is Telling You 02:27:11 The Best Exercise Routine for Healthier Mitochondria 02:28:11 Which Blood Tests Can Reveal Your Mitochondrial Health? 02:30:14 The Personal Loss That Changed Everything Follow Dr Martin: Website - https://link.thediaryofaceo.com/BqY0OhF Substack - https://link.thediaryofaceo.com/4aOc0rk Metabolic Psychiatry and Ketogenic Diet - https://link.thediaryofaceo.com/GexHJoI X - https://link.thediaryofaceo.com/Fs8WGvj Instagram - https://link.thediaryofaceo.com/BsNZ7vH You can find out more about Dr Martin’s upcoming book, ‘Energy’, here: https://link.thediaryofaceo.com/5jW5yUA The Diary Of A CEO: ◼ Join DOAC circle here - https://doaccircle.com/ ◼ Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook ◼ The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt ◼ The Diary Of A CEO Conversation Cards: https://linkly.link/2hm7r ◼ Get email updates - https://bit.ly/diary-of-a-ceo-yt ◼ Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb Sponsors: KetoneIQ - Visit https://ketone.com/STEVEN for 30% off your subscription order Cometeer - https://cometeer.com/DOAC use code DOAC for $20 off Bon Charge: https://boncharge.com/DOAC for 20% off
"This is incontrovertible evidence that graying of hair is reversible and [music] it can be pre-fast. >> Wow. >> And there's more. So, we all walk around with our biological [music] history encoded in ..."
">> In a nutshell, what is it that people are looking for when they listen to this subject of energy? >> Yeah. I think that people want to understand what is energy, and how can I have more energy? >> ..."
">> And and who are you and why did you commit your life to this subject? >> I'm a regular guy who with, you know, lived experiences who who's gone through some tough things that have taught me lessons..."
">> You have a PhD in mitochondria. >> Yep. My PhD was in mitochondrial biology of aging. >> I mean, there's a an image here in front of me. Some people will just be listening, so we'll try and explain..."
">> Who should care about the mitochondria and why should they care about it? >> Anyone who cares about their energy. Right? About having enough energy to do what they really care about. Uh >> [clears ..."
">> Where do we need to start to understand? Cuz the outcome I want from this conversation is I want to live my life with more energy to do the things that I want to do. And I imagine the people that a..."
">> has the mitochondria got to do with all of this? >> Mitochondria are basically little resistors, right? And and they are what allows the flow of energy through the system. >> Have you got a picture..."
">> Am I right in thinking that they used to be bacteria? >> They are. Yeah, they did Yeah. >> What what is that story? >> [laughter] >> Cuz I think someone said that to me before on the show that our ..."
"I've heard you say that most diseases or disorders can be explained by understanding energy resistance. Give me a a disease that's linked to energy resistance. >> The clearest is what we call insulin ..."
"it sounds I mean, I don't know much about cancer, but cells dividing out of um control seemingly randomly >> Yeah. I think that there's a very good chance, if you look at the biology of cancer and wha..."
">> So, is there any understanding as to how those kind of cancers are caused? Like, what what causes that moment where, you know, you talked about the Warburg effect? What causes that? >> The cancer c..."
">> Mhm. >> Right? Diabetes is a major risk factor for developing cancer. Why is that? I don't think there there are good explanations out there based on like the molecular framework of of disease and ..."
"smoking also is carcinogenic. It's cancer causing. And through the lens of the mitochondria, how could something like smoking be cancer causing? >> Yeah. It's clear that in cigarette smoke, there are ..."
">> Well, then what's what's going on with aging? I've got two women in front of me and they have two different colors of hair. Now, let's just pretend for argument's sake and for the sake of this expl..."
"then the X axis, the horizontal, was time. Yes. On the far right is now, right? This is now, this is a year ago. And then we labeled all the months. And then we asked people and we asked this lady put..."
"thing, but it did make me think cuz you you added a layer of nuance there, which is about the mind. >> Mhm. >> Like if I go through my life um with a more resilient mind and you get that bad email and..."
"which is just you get the email, you feel a little bit of a spike, but 5 minutes later you're fine. >> Yep. >> And then there's the more chronic type of stress where you're waking up every day with th..."
"thing cuz I'm really struggling with like understanding it? >> Maybe one good example to to frame this is exercise. >> Yeah. >> All right? When you start to exercise, there's increased resistance in y..."
">> Coming back to this gray hair thing. So, if if we consider gray hair, my hair going gray, to be the last domino that fell. So, like the symptom. >> Yeah. >> Then what is what are the what what is t..."
"body's going to commit all the the energy I have to getting away from this lion and it might say, "Listen, Stephen, we're not going to repair the skin next to your eyes. You're going to get a couple m..."
"then? You know, you said about stress. Okay, I'm going to live a less stressed life. >> Yeah. It seems like there's a few things that we know makes organism more efficient. One is exercising. >> Okay...."
"uh I've got coffee here. I've got some alcohol here. I've got the sugar. What I consume, how does that impact the efficiency of the energy flowing through my body? >> Yeah, great question. Uh alcohol,..."
"dementia weirdly because I don't really know a huge amount about Alzheimer's and dementia, but I know that something clearly goes wrong in the body that produces these plaques. >> Mhm. >> And you know..."
"three diabetes? Cuz I've just heard that phrase quite a lot recently. >> Yeah. And So, my hunch is that Alzheimer's and dementia more generally is a disorder of energy. And specifically, it's a disord..."
">> Yeah. I did look at the stats there on the tribes in Africa and it says when researchers study indigenous groups such as the Hadza hunter-gatherer tribe in Tanzania or rural agrarian populations li..."
"on how to stay focused and high energy, let it be from the greatest pound-for-pound fighter of all time, the guy they call Johnny "Bones" Jones. Johnny is a co-owner of our show sponsor KetoMojo IQ al..."
"autophagy, all these words that I've heard. If you were giving me advice on everything you know about how to create a body that is very, very efficient in how I deal with the energy that I have, what ..."
">> I mean, I'm I'm a big big fan of survival documentaries. And one of the most remarkable things you see in survival documentaries, I'm even thinking about some that I've watched, is people can survi..."
"says that this idea that breakfast is the most important meal of the day came from an advertising campaign that was designed to sell cereal and bacon. Um before the industrial revolution, breakfast wa..."
"thing that influences where energy goes in the body, how it flows. Um and just maybe to close the loop on that example, like when you're sick and you're fighting an infection >> Yeah. >> I had a a bea..."
"clip. It's a clip of Kevin O'Leary talking about this idea of signal and noise. And he's referencing his experiences with Steve Jobs who he used to work with and also Elon Musk. >> Look how wildly suc..."
"Uh they're able to, you know, see something, hold that vision so strongly, and then mobilize others, right? And then new things become uh possible. I think that's what great leaders do. And I I now ap..."
"actually being magnets for energy. You think about going to the moon, the moon pulled energy towards it, so we found ourselves to the moon. And actually, if you bring that down into your own life as l..."
"on brains of dead people have found that those with a greater sense of purpose have more efficient mic- mitochondria? >> This is this beautiful study in it was run in Chicago. Every year, people would..."
"isolated, we did a study recently to look at the energetics of mental stress. When you feel like you're being pulled aside and judged, and right? What does that do energetically to the body? And and t..."
"belly fat? >> Visceral fat, yeah. >> Yeah, you're going to get belly fat from this. >> Yeah, when stress hormones are up, right? And you're increasing blood glucose increasing blood lipids, if the res..."
"I guess it's going to lead at some point to disease. >> Mhm. What the best studies show on this is when you have high level of this energetic stress marker, this protein, you're more likely if you fol..."
"asking that is listening to this now is how do I prevent GDF15 or whatever it's called, this stress cytokine thing that goes and docks in my brain? How do I prevent it from floating around in my blood..."
"something there that methylene blue can help relieve energy resistance in the mitochondria. NAD+ is probably the best supported intervention to reduce inflammation. Also, it's an electron carrier. So,..."
"terms trusting the wisdom of your body? Like what does that mean for you? >> Uh-huh. It means recognizing that I am the the energy that's flowing through this thing and this thing is nature. Like we a..."
">> Whoa. >> Whoa, it's on your face. >> This is a my bun charge face mask. I've been wearing this for some time now. They are a sponsor of the podcast. I put this on for 15, 20 minutes a day. I can si..."
"know about from you, which was even more discussed, was about red light therapy. Red light therapy as a support for your mitochondria. >> Interestingly, the red light therapy is a pretty big thing now..."
"bloody red light then? >> If you're deficient in that in that way, that might be good. Uh that might also offset, you know, the the natural order that your body has has created. >> Oh, what do you mea..."
"you close your eyes earlier when I asked you to kind of feel inside. This is a good analogy for I think what it means to kind of listen to our energy. And maybe we could do a little exercise if you're..."
"talked about earlier, if someone wants to maximize mitochondrial biogenesis, what is the sweet spot for training? Is it strictly zone two cardio or high intensity interval training or resistance train..."
"was, "Right now mitochondrial health feels a bit invisible. Are there any accessible reliable tests like ATP blood tests or specific biomarkers that a normal person can use to accurately measure their..."
"tradition on this podcast where the last guest leaves a question for the next guest not knowing who they're leaving it for. And the question that has been left for you is what is the most difficult th..."