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Sam, I think today we should talk about somebody who is one of the most important founders in the world, one of the most brilliant founders in the world that nobody talks about.
Sam, I think today we should talk about somebody who is one of the most important founders in the world, one of the most brilliant founders in the world that nobody talks about.
I don't even know how to say this guy's name properly and he is one of the most important tech founders in the world.
His name is Dennis Hassabis.
Is he currently the guy who's like warning people?
Is he on a like a podcast tour warning people? No, no, no.
He's pro AI so he's not warning people.
No, then I don't know anything about him. Enlighten me.
>> [laughter] >> Okay, so this guy is Dennis the Menace is what I'm going to call this guy cuz this guy is an absolute animal.
Okay, so so I watched this documentary called The Thinking Game.
It's on Prime Video if anybody wants to go watch it.
I'd heard good things from some smart people so I thought, "Okay, let me check it out."
And let me just first lay out my case for Dennis as Billy of the Week because he's kind of legendary.
he's kind of legendary. Okay, so I didn't understand how much of a prodigy this guy was and this was a documentary that was like, you know, pretty straightforward but like this could have easily been a movie like The Social Network because
The Social Network basically covered the most transformative young brilliant founder from the kind of 2004 to 2010 era which is Zuck and it talks about Zuck in college and how he's this kid and you know, all the ups and downs he goes through trying to build this thing. Dennis is maybe that guy now and him and
Dennis is maybe that guy now and him and Sam Altman, they're both basically like two guys who are creating the most important technology of all time.
You think those are the two guys? Those are the guys?
Well, Elon would be the other, right?
So Elon's the obvious other person that needs a movie and has a crazy life but this guy I think is the most you know, underrated less talked about for who he is. Okay, so who is he?
He started this company called DeepMind.
DeepMind got bought by Google and DeepMind is basically Google's AI play and the DeepMind team which was basically a research team that was building AI is the reason that AI exists.
It is the reason that ChatGPT exists.
It is the reason Elon is interested in AI was very much because Elon met with Dennis and basically Dennis big dogged him a little bit.
He was like, "Oh yeah, I'm working on the most important thing ever."
And Elon who's building rockets and electric cars, he's like, "I'm saving the planet. I'm going to space. That's my portfolio."
And Dennis said, "Well, what we're building will be the most important invention humans will ever make.
It will be the last invention.
It's artificial general intelligence.
So a computer that can think and learn better than humans."
And the reason why this is called the last invention is because once you invent an artificial general intelligence, it's basically like it's own little species.
So it's computers that can think and learn, they will then do the thinking and learning and inventing far faster pace than we will.
So they'll invent all the new [ __ ] after that.
He has that conviction throughout the documentary.
And he's had it since he was a kid.
Okay, so the here's the here's the cool story.
That's the you know, the very basic setup but here's the story.
So he grows up, he's got these like hippie parents.
His dad's like is a musician and they look like very like bohemian.
He gets into chess and by the age of six he is one of the best chess players in the world.
Amongst all humans or six year olds?
So first he wins the under eight championship when he's only six in in Europe.
Then and he is at one point he's ranked the second best chess player in the world for his age.
So he's like elite elite chess player as a young kid.
And he uses his chess he would go to the his parents are basically driving to these chess tournaments he would win as this and he looks tiny.
Even now he looks like baby faced.
He looked like such a little kid when he's sitting there at these tables and he would basically go win prize money and then he used the prize money to buy his first computer. Okay?
So chess gets him a computer.
When he gets a computer he starts making games on the computer.
He builds a chess game, builds other little games and he starts a hacking club with friends at school and he's basically like, "Wow, computers and chess like this is my life."
If you had a character stereotype for a good movie character who's like, you know, a James Bond villain or a mega genius, this is how they all start.
The story is all the same.
>> way, he he tells the story of this incredible origin story.
So he goes, "My parents took me to this tournament of 300 of best players in Europe and it was like on a mountain in a church."
And it shows the church and it shows 300 you know, 150 chess tables lined up.
300 players are going to be there.
And he's only I don't know, he's eight years old or something at this point.
He's tiny and he's playing against the like the Danish national champion, a 30 year old man is playing against him.
And he describes it basically this the chess tournament was no timer.
So this turn this game with this 30 year old dude goes for 10 plus hours and he's just playing him and he's like, "I'm pretty sure it's a draw but this guy's not conceding that it's a draw so I just have to keep playing."
And he's with this guy just wearing out this little kid over hours and hours and hours.
They only have like five pieces on the on the board and it's just like a stalemate basically but he won't give in.
He won't say it's a stalemate.
And he decide he describes how at the end basically this guy kind of like tricks him a little bit and he ends up losing when what should have been a stalemate.
He makes one wrong move at the end and the guy laughs at him, stands up and laughs and says, you know, you should it should have been a stalemate.
You should have just done this and you would have it would have been a stalemate.
Like rubs it in his face basically.
And he's so upset at this tournament and that this like kind of grown man humiliating him.
He looks around and he's just like, "What am I doing?"
He's like, "That was a horrible experience."
And he goes, "If you took the 300 people in this room, the brain power in this room that we're just spending on this like, you know, a 10 hour tournament here, we could cure cancer."
And he's like, "Forget chess.
I'm not going after chess anymore.
Like I'm so done with chess after this bad experience.
I'm going to go for computers.
I'm going to try to figure out how to harness the brain power of humans and combine it with computers.
How do I get computers that could think?"
And and the documentary is called Thinking Game because they interviewed him when he was like a six year old and they're like, "So why do you" like a TV network was like, "Why do you love chess so much?"
And he goes, "It's just it's a good thinking game."
>> [laughter] >> What a fun hang. What a fun hang.
Could you imagine your boy played with him?
>> [laughter] >> Okay, so listen to this from boy wonder.
So he gets into Cambridge but he's too young to go so he has to wait a year to go to Cambridge cuz he decides, "I'm going to go to Cambridge. I'm going to study AI."
He's like 14, 15 years old at this point.
And in his gap so he's like they need him to wait a year.
He can't go till he's 17.
So he says, "Okay, why don't I try to get a job?
I'll work in the meantime and I'm not going to do chess tournaments.
I'm going to do something with computers."
And so this company called Bullfrog which made like the most popular computer games at the time in Europe.
They were the number one production company of games. They held a contest.
And it was also cool to see like gaming was so new at the time.
The CEO of the gaming company was like there was no recruiters.
We couldn't be like, "Hey, go get us the best game programmers."
There were no game programmers.
It wasn't even a job yet.
And it just reminded me of like what the frontiers always look like.
It's like little signals of you're in the right spot is when there's not even recruiters for the thing.
There's no agencies yet for the thing.
There's no name for the job.
And for context by the way, he's 50 years old now.
He's 49 so we're talking the eight late 80s. Right.
Yeah, yeah, long time ago.
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So he enters this contest, he wins and he gets a job there.
And the first game he works on is the Did you ever play RollerCoaster Tycoon? Of course, yeah.
So he was built They Europe had the equivalent called Theme Park and he built Theme Park with this guy.
It became a smash hit when he's 16 years old.
And his job in Theme Park, he was to not building the the park builder but the guest the guest logic. So AI basically.
It's like you're going to have a thousand guests walking around but they need to do sensible things.
Like a thousand Sim characters like decided to go on a ride.
Got Yeah, that are going into your theme park.
So he he's like and he and so they were like, "Oh, just make them walk around in a random path."
But he's like, "No, no, no. This is AI. I want to work on AI."
So he goes he makes it so that if you make the roller coaster too crazy, they'll puke.
Espe- and the odds of them puking go up if there's a burger joint next to the theme next to the roller coaster.
And so he creates all this logic that was not in games at the time.
Like this like very intelligent logic around the autonomous characters in this game.
And the even the people there were like, "Dude, why do you care so much about this?"
And he says at the time he's There's a line in the movie where he goes, "Today the whole world agrees with something that I knew 20 20 plus years ago that AI is the most important technology that we're ever going to build and that that was the only thing that was worth working on."
So even at the game company he's working on AI.
Okay, so he gets he's now 17. He can go to Cambridge.
The guy who owns the company offers him a million pounds to stay and he's like, "I'm a poor kid. I'm 17 years old.
He offers me a million pounds."
It's more than a million dollars.
And this is back in the like >> it's eight million eight million USD.
Yeah, like a huge offer just to stay.
And he's like, "No, I want to go. I want to build AI."
So he turns it down and he stays broke and he goes to college.
And at college he basically, you know, meets this other guy, the only other guy he knew that was equally obsessed with AI and neuroscience and like how the mind works and then teaching computers to think like a human mind.
And so he >> you were going to say that he like partied hard and He did actually.
He's like and hooked up with tons of girls.
>> He's like we would drink beers and we would play foosball and we would talk AI. He's like we were crazy.
>> [laughter] >> Okay, so then he's he decides at some point that he's going to start this company.
And now nobody really believes in AI at the time.
In fact, in the scientific community AI was not a thing.
Cuz it's not science really.
There's no like testable hypothesis that you could go do.
You couldn't go into a lab and and do AI.
The entrepreneurship community also didn't really respect AI. It's this sci-fi topic.
No there's been no commercial companies doing this.
So he's there's nobody who believes in this.
Well, guess who believes when nobody believes?
Guess who loves a good old contrarian bet? Thiel.
Thiel backs if Thiel becomes the first backer of DeepMind. >> Are you kidding me?
No, so how legendary is Peter Thiel that he's the origin funder of DeepMind too.
>> I I think that people talk about this, but I don't think it talks about enough where I think Tim Dillon's a comedian where he was like everyone thinks the president of the United States is like most powerful, but there's one person who's never around.
You can't see him, but he truly runs everything and that's Peter Thiel.
And he was saying that like at Trump's inauguration it was like J. D. Vance who's a Thiel guy. It was all the CEOs.
Thiel guy, Thiel guy, Zuck, Thiel guy, you know, and it was like Peter Thiel is the guy.
And then I recently read a whole bunch of old quotes from him.
And it's just like everything he says is timeless and has been true so often. He's like a city, dude.
He's like a place that people are from.
>> [laughter] >> It's very strange.
>> Oh yeah, Zuck he grew up in Thiel.
Oh Ethereum, you like that?
Well, he got grew up in Thiel.
Oh yeah, yeah, that that's true too. And then Elon Musk, yep.
He actually first company merged with Peter Thiel's company and Peter Thiel was the CEO.
So a lot of times it starts with um was it was it Plato or Socrates where like it like well, Socrates taught Plato.
Plato taught Alexander the Great and also Aristotle.
And it's sort of like there's like this one person that's like the the lineage. Yeah, it's very strange.
[clears throat] So Thiel becomes the backer.
The second backer I think the second significant backer was Elon Musk.
So Thiel tells Elon about this. Elon meets Demis.
Demis says that that big dog line and basically like I'm working on the most important thing in the world.
Elon you know, is like wait a minute, what's going on here? He ends up funding this.
Okay, so he gets a little bit of funding from some some crazy believers.
And now the part of the movie that I think is just incredible is showing them building this monster that is AI.
So when they're when you say build, is there actual physical building as well?
So so what they would show No, so at at the time it's them on a whiteboard with really complicated math equations talking about well, what if we took this technique from deep learning and we merged it with this this technique over here about neural nets and like you know, what if we could get something new?
And that's what they did is they they got Q star plus deep learning you know, they combined these two different ways of learning.
Don't ask me what any of those words mean.
But the thing they show is a little TV screen with the Atari game of Pong.
And so it's so funny that this whole thing starts with Pong and it starts with games.
And so much like you get the most brilliant people in the world staring at this Atari game trying to be like, how can we teach the computer to play this game?
And he he like because he grew up on chess and he was super competitive and the games were how he learned to think.
He's like maybe games will be how the computer learns to think.
Because games have rules, they have rewards, they have like clear definite you can play have a a board where you can see all the information and you could do it a bunch of times and get better and better and better and better at it.
You can run a lot of simulations very quickly.
So the rate of learning just like how he basically was like the way kids learn is games.
So maybe that's the way we can build a child-like computer program to also learn.
I think one of his breakthroughs was like when they played the Asian game, right? Uh go.
Yeah, so before that it starts with Pong.
I didn't actually know this and they they basically said, look, don't tell it anything about Pong. Just tell it one thing. Score go up is good.
So at the beginning they show it and they're all watching it.
They're all just like sitting there watching and the the computer hits it like the game hits it and then their AI player like doesn't even move its paddle. It's like, uh down one.
Next time it like moves its paddle the wrong way. We're down two.
Next time moves its paddle the wrong way almost recovers but misses it. Down three.
And then it hits the ball once and they're all like, but then it still loses the point.
And it basically over you know, it starts out terrible.
By a hundred games it's competitive.
By 200 games it's like as good as the best humans at playing the game.
And by 500 games it's never losing a point.
And they're like, okay, that was remarkable. Let's carry on.
And so they had this first objective which is let's without telling it because again the goal the goal was he goes, what is AGI?
It's it can think and it can learn.
So we can't just tell it the rules.
We can't just tell it how to win.
We can't give it strategy and then it executes it. No, no, no.
It has to figure it out itself like a kid learning how to walk and it stumbles and it starts to figure out, oh if I put my center of mass here, that's how I walk.
So they wouldn't tell it anything about the game except for whoever has the higher score at the end, that's a good thing. Go for it, computer.
And so they would and then they they had it learn like 50 games.
So then the next one was like Break Breaker.
If you ever played that game on Blackberry where it's like breaking bricks and it and it says the same thing. 100 games, terrible. 200 games, pretty good. As good as most humans.
500 games, it's unstoppable.
And it figured out this strategy in Break Breaker where you tunnel in through the sides and then the the ball will just keep bouncing on the top and break all the bricks on its own without having to hit you.
And it's like, okay, that's cool. Next let's do chess.
So then they show it doing chess and the one of the kind of like the first aha moments was it started to invent its own strategy a little bit. But just a little bit.
Like, oh it's got its own style.
Okay, that's kind of interesting.
It's got its own little attacking style. That's pretty cool.
It beats Stockfish which is the best chess program out there.
And they're like, well, that's good cuz Stockfish beats all the pros.
If this beats Stockfish, that means it's the best at chess.
And then they went to go.
And so go I didn't entirely understand what it almost looks like Chinese checkers, but it sounds like it's more complicated and they claim that it's the most complicated game on earth because it has the most permutations on how you could possibly win or lose. Right.
There are more board configurations in go than there are atoms in the universe.
So you can't like just think it through.
You know, there's too many combinations.
So you have to be actually fluid that in any situation you're in be able to figure out the right move.
So people had always thought go is too hard.
No computers had ever beaten go before.
And so they start and they this is called they created this program called AlphaGo.
So AlphaGo basically what they did which was this is kind of nerdy, but I I liked hearing how they did it actually.
They gave it a thousand or a thousand or a hundred thousand games from strong amateur players.
They said, here's a hundred thousand games, learn from this. Past games.
So they gave them like like the the play-by-play.
Uh yeah, like the move-by-move thing. And it learns all that.
And then it said, cool, based on what you learned, now play yourself.
So based on what you know, you play yourself.
See if you can get better.
And it played itself like a million times.
Okay, so that's kind of interesting.
Maybe that'll get a new result.
So they go to Korea for this test.
They're like, we're going to go play this guy Lee Sedol.
And Lee Sedol is you know, a grandmaster go player.
He's one of the best players of the past you know, two decades. He's the man.
And they show them like getting off the plane and there's like hundreds of photographers taking pictures.
Like today the computer versus man, man versus machine.
And like I didn't actually see any of this when this was happening.
I don't know if you did either.
But like again, in this small corner of the Dude, this storyline is as old as John Henry.
Do you remember John Henry who was like, you know, the strongest man >> man who was did you use it the jackhammer through the mountain trying to race the the new steam engine who can like pile through stuff and he works and he's trying to beat the steam engine and he works so hard that his heart explodes.
And it's like that's like the story. It's the the legend.
That's basically what happened except the guy's mind exploded.
Yeah, so that's this like storyline is perfect.
So they sit down and the game is going as usual.
And they they have a line from Eric Schmidt.
So Eric Schmidt is from Google.
He was the former CEO of Google.
And a super technical guy and he and Google had bought DeepMind at this point. Dude, I saw the price.
One of the greatest deals of all time potentially.
So they bought it for I think 400 million pounds.
So it was like you know, 500 something million dollars.
And there's a great line from Demis in this.
I don't know if you saw this part where he they were like, his investors didn't want to sell.
And he goes he said this line that I really like it was kind of a frame breaker for me.
I don't I I don't think most people when they listen to this line would even think twice about it.
But for me it was a little bit of frame breaker.
He was basically in like a frenzy.
He's like, this is so important. There's so much to do. My life is only so long.
I want to see this happen.
And he's like, we have so much to do.
If we can just get this funding and be left alone to go do what we needed to do then I might actually get to see this thing in my lifetime. And that's what matters.
And he's like, what's a few billion dollars for five years extra of my life getting to work on this?
He was like, would you trade a few billion dollars?
He's he goes, I could sell for a few extra more billion and make a billions dollars, but let me ask you something.
If you're going to die, would you spend billions of dollars to live an additional five years? Of course you would.
And that's what he said he was going to do here. It's such a good line.
I I actually someone changed my perspective on having children.
Someone was like, do you think you're going to love your kids when they're born? I was like, yeah.
He's like, well, then why wouldn't you have them sooner so you have an additional like life with them?
>> [laughter] >> He has another line later that's kind of like this.
He goes he was talking about like what a new breakthrough that they were going to have and he's like, it's going to be the most exciting thing ever. How will we get sleep?
I won't be able to sleep.
And he was just like that fired up 10 years into the mission.
And so I just thought like when people talk about mission driven, this is what they mean.
When the guy is like, there's so much to do.
I don't know if it'll happen in my lifetime.
The most exciting thing in my life is if this happens while I'm still alive.
I will do everything in my power to make this happen while I'm still alive.
And I thought that that was just like a next level of mission driven excitement.
I want to read you a cool quote.
Um okay, so I'm reading this book. Can you see this?
It sounds silly, but hear me out.
>> The quick and easy way way to effective speaking by Dale Carnegie. Oh, very cool.
So Dale Carnegie, you know, wrote famously wrote How to Win Friends and Influence People.
Uh he's actually more famous originally because he created the Dale Carnegie speaking program.
And so they had locations all over the country and hundreds of thousands of people went through his programs.
Including Warren Buffett who says it was the most important class he ever took and he had the diploma from the speaking class on his wall next to his office, not his college diploma, you know.
>> even taught he was a Dale Carnegie instructor.
And uh there's this amazing quote.
And so basically Dale Carnegie, one of his premises is that public speaking, he calls it the uh the royal road to self-confidence.
He says, "If you want to be a more confident person, you should actually learn how to public speak because when you control the minds of of many men, you control yourself, you know, it makes you more confident."
And one of his um axioms or whatever for how you get better is you have to envision the end goal.
And he has this amazing quote from William James who's like it's like the godfathers of like modern psychology.
And there's amazing quote of William James.
He says, "In almost any subject, your passion for the subject will save you.
If [snorts] you care enough for a result, you will most certainly attain it.
If you wish to be good, you will be good.
If you wish to be rich, you will be rich.
If you wish to be learned, you will be learned.
Only then you must really wish these things and wish them with exclusiveness and not wish 100 other incompatible things just as strongly."
And his point being is whatever you truly want, if you want it bad enough, your passion will carry you enough to acquire all the skills and have the determination to see it through the end.
And I was going to I wrote this down that this guy you see it from the beginning and where he is now, this quote applies to him. That's great. Okay, little segue.
Have you ever seen the Tony Robbins TED Talk he gave?
It may Yeah, yeah, probably.
I've seen many of his talks.
So Tony's normal talks, like his seminar, is like a four-day 12 hours a day on stage thing.
So TED Talk is 18 minutes.
So he gets on stage, he's like, all right, like I usually talk for 12 hours at a time.
Let's see what I can do in 18 minutes.
And he gets to this point in the talk, he's like, "What stops us from getting what we want?"
And then people are like, "I I don't" He goes, "I don't have the" And people are like, "Time."
He's like, "Yeah, all right, time. I don't have the money. I don't have the skills.
I don't have the network.
I don't have" And he writes all these resources that you lack down.
And then one guy in the crowd goes, "I didn't have the Supreme Court justices."
And he looks through the darkness, he's like, "Who said that?" >> Yeah, Al Gore.
It was Al Gore who had just lost the presidential election.
And I remember in Florida there was a recount and the justice he was like two justices short or something like that.
And everybody has a big laugh and then Tony says, he goes, "You know, I don't think that's why you lost because I saw you yesterday on this TED stage talking about climate change.
You know, Gore is like super passionate about climate change.
He was like one of the big advocates for climate change.
And he goes, "If you had done if you had talked like that in your presidential debates, you would have never needed the Supreme Court justices.
You were on fire yesterday.
And I didn't see that when you were debating Bush."
And he basically says, he goes, "The only resource you need is resourcefulness."
He goes, "Because look, if you're just like you said, if you're just lit on fire to do something, you just ask yourself the following question.
Like, "If I'm determined enough, if I'm charismatic enough, if I'm charming enough, if I'm playful enough, if I'm creative enough, if I am like motivated enough, I'm persistent enough, can I not achieve anything I want?
Can I not overcome all those things that I lacked?" It's like, of course.
Like, you didn't have the resources.
You didn't have the money.
Well, but if you're determined and you're charming and you're persuasive, you'll go get the funding.
You it's like this master skill that's underneath.
And so I find my I I often I actually catch myself doing this all the time where I feel like I lack something and I'll literally go say that almost like an like an affirmation.
Like, "Well, if I'm playful enough and I'm determined enough and I'm charismatic enough and I'm persuasive enough and I'm determined enough, like can I not can I not get this thing I want? Of course I can."
Like, "Oh, they're closed?
I could probably get them to open." "Oh, this guy said no?
I could probably get him to say yes." Right?
And like each one of those things >> [laughter] >> that's like just like this universal skill we all have if you remind yourself. >> That's pretty badass.
I don't even think you need to be charming charming.
This guy Demis um he he was pretty black and white, but when I listen to him, I'm like, "You're an unstoppable force.
You you care about this so much."
He is what Paul Graham calls a fierce nerd.
I think that fierce nerd essay is actually Hall of Fame level for Paul Graham.
And you see it when you see somebody like Demis and how competitive he is with foosball and chess.
And then he's also that way with trying to win the like protein folding problem.
All right, back to the story.
So they're sitting there with the best Korean Go player in the world, Lee Sedol.
And there's this move, move 37.
And I think if they write the book of humanity or the movie of humanity, move 37 is like the uh-oh moment.
It's like the moment in movies where, you know, in a rom-com it's when the guy bumps into the girl and she drops her papers on the ground and they pick them up and they look each other in the eyes. It's like the spark.
This is the spark of like where AI really took off. And it's move 37.
So basically they're playing Lee Sedol.
The expectation is Lee Sedol will win cuz Go is so hard and he's the best.
But we'll put up a good showing.
We'll be as good as the best players against Lee Sedol.
And in move 37, the computer did something and right away the announcers are like, "Oh my. Oh, what is that?"
And Lee Sedol, you literally they show him like sweating and thinking and he's like, "What the hell just happened?"
They go and they go, "I think we might have just seen an original move by AlphaGo."
And Lee Sedol is like just he doesn't know what to do.
He's like really perplexed by this move.
They go, "No human would have made that move."
And it was the first time that it wasn't just pattern matching what like let's mimic what a what a human would do or say, but less good than a human would say or do it.
Or maybe it's a little bit faster cuz it's computer, but it's still doing what a human would do.
It was the first time it was like, "That was novel.
That was a creative breakthrough." And it beats Lee Sedol.
It's like when the like in a horror movie like the robot turns to you and says, "I'm in charge now."
Like this is that moment. Exactly.
And so I did I had never actually seen the clip.
And the way the movie shows it, I think is wonderful.
So then right afterwards Eric Schmidt's like, "Holy shit."
And he goes to Demis and he goes, "What's next? Where does this end?"
And he goes, "When we beat the Chinese guy."
I didn't even know about this part.
It's like then there was a Chinese guy who was the actual number one ranked player in the world.
They go to China to play this guy.
And now it's like, "What's going to happen?
This computer just beat Lee Sedol.
Is it can it beat the Chinese guy?"
And I just love that they even called him the Chinese guy.
It was like the most relatable thing that this absolute super genius with like a 10,000 IQ said.
I was like, "Oh, he's just like me.
He just We would just call him the Chinese guy." Like that that was cool.
And so they go and they play.
Had you ever heard about this?
No, so I just If you go on YouTube and type in move 37, there's videos with hundreds of thousands and millions of views and it's all like, for example, retelling the story of move 37.
Or there's Magnus Carlsen uh talking about like how move 37 teaches you about XYZ.
Like it's it's become like an acronym or not like an analogy for like um you know, when this It's like the four-minute mile, right? Yeah, exactly.
It's like exactly is what it is. The four-minute mile.
Like it's just a phrase that doesn't even mean move 37 anymore.
It's go grown beyond that. Totally, totally.
I see your little public speaking brain is picking up on all these little uh you know, magic the magic of of tiny words, huh? Thanks, Dale. Thanks, Dale.
>> [laughter] >> Thanks to our guest today, Dale Carnegie. Thank you.
Um okay, so then it goes to they play the Chinese guy.
Now here's the crazy thing about playing the Chinese guy. AlphaGo is whooping ass.
And it's like putting the pressure on the number one player in the world.
>> smoking cigs while he's doing this cuz that's why he's winning?
He's actually a pretty young looking guy.
But the crazy thing is as he starts to put the pressure on the Chinese guy, they cut the feed in China. No way, really? >> is that?
They cut the feed of the broadcast.
They're like, "No, we will not show our We will not lose face like this."
And they call that in the movie.
They're like, "This is like the Sputnik moment where China was like, wake up call. We're getting into AI."
And so this actually triggered the AI race for why China got so into it and how they cut the feed. So dramatic.
I thought that was incredible. >> That's crazy. Okay, awesome.
Okay, so then they go they continue with games. So let's fast forward.
They do StarCraft next, which StarCraft is interesting from a Why why StarCraft?
Because both players are playing at the same time.
So it's not turn by turn.
Like you go Is StarCraft like a fighting game? I don't know what it is.
Yeah, I think it's called like a a MOBA or whatever.
It's like basically a game where you know, you have a map.
It's like Grand Theft Auto a little bit, but >> You have a base, they have a base, you got to attack their base with characters.
You got to move them around the map. There's a fog of war.
The whole map is not revealed.
Both players are playing simultaneously. So now it's even harder.
You you're acting like you don't know what you're talking about. I don't play that.
But anyway, so there's this fake character. Here's what he does.
[laughter] I don't play StarCraft, but I you know, I've been around enough dorks to know enough.
All right, so it doesn't actually beat the best StarCraft player in the world. That guy wins.
Okay, but it was a good good showing anyways.
Then I think what's what's just what's the next step?
What's the next step that really stood out to me?
There's this one last part about protein folding.
So are you are you familiar with what they've been doing with this?
Uh all I know is that no one had ever solved it and basically within days or weeks or something like that, they solved something that took 50 years to get up to that point in progress.
>> it took years, which is cool.
I didn't actually realize this.
So, so Demis is basically talking about they're like, "All right, we did good in games, but he's like, "Before AGI, he's like he's basically like AI-assisted science is going to be the thing."
And I don't think this gets talked about very much nowadays.
Like maybe the pi like maybe AI could cure cancer.
But this guy's seriously like, "No, AI should cure cancer." And all this stuff.
>> clear how math can or math or that type of like uh >> How chat GPT cures cancer.
It's like that link seems very wrong.
>> you need more data and more effort?
Like like it's it's it's as if like in order to cure cancer, you're just like let's throw these 50 drugs at them.
Oh, that one kind of worked.
Let's like soup up the drug and throw it 50 more times, you know, that's sort of how in your head you think cure cancer, not like can you math your way out of it. Correct.
Now, what I've realized in watching this and hanging out with AI people is one of the most important things in the world is basically prediction.
So, I remember I invested in this guy who was self-driving car entrepreneur.
He had worked at at the Uber self-driving car team, and he took me to this little garage, and he had this like golf cart that he had rigged into >> or 18, right? This was pre-pandemic. >> that maybe.
Yeah, I don't remember I met him at I don't know but that was that was probably the time.
It was yeah, right before I started my funds.
So, 2018-2019, you're right.
And um he drove me around in a self-driving golf cart in a self-storage facility.
So, it's like you get a peek at the future.
You're like, "Whoa, that was amazing."
Um this is you know, before Tesla had it and whatever.
But like you know, it wasn't perfect.
It could only do it in a very controlled, you know, environment.
But he basically said like, "Look, everybody's working on this knows there's these like four or five steps of self-driving."
And I didn't I don't remember all of them, but one was like predict you know, so it's basically like vision.
So, you got to see the world.
Then, based on what you see, the next step is prediction.
So, okay, I saw that that car was right there.
Where will it be in 2 seconds?
I need to predict where it's going to be.
That's the whole like basis of self-driving is planning, prediction, there's like an action step, whatever. This is like five steps.
So, that that kind of planning and prediction step is the key to how AI affects all these industries.
So, chat GPT is planning and prediction of what is the next token or let's just say word.
What's the next word that would probably go in this sentence?
You know, the um roses are red.
I think it's going to be red because I've seen roses are red so many times that my my prediction score very confidently would say, "The next word in the roses are is red." Okay, great.
How do self-driving cars work? Same thing.
If I see a car there, my prediction is it's going to be here in the next 1 second.
So, therefore, I need to do a new action.
The same thing applies to science and curing all these diseases, which is you need to know what a protein structure looks like.
Based on the shape of the protein structure, you can then if you can predict the protein structure, then it's not so hard to figure out what should you attach to it to either like destroy that protein or uh soup it up and make it more strong or whatever, right?
You know where to bind on the protein.
Okay, so I didn't know about this thing, but this is called CASP.
So, CASP is this competition that've been going on for years.
And it's basically the Olympics of protein folding.
So, if you do like a a sequence, you're like amino acids.
It's oh, it's got this amino acid, this amino acid, this amino.
You get just 10 amino acids.
Cool, you know what's in it, but you don't know what it looks like. Okay?
You don't know the the structure how it's folded up into this like little tiny knot. A very unique structure.
When you say folding, figure out the shape of the knot. >> of it.
And you need to know the shape in order for what?
To design a drug that's going to do anything to it.
>> So, you could you could kill it or grow it or shrink it.
Like imagine I said, "Hey, you're going to park this car at this address." Cool.
But if you don't know what the garage looks like, you're just going to smash into this house, right?
Like you might know the location of it, but you don't know where to park the car.
So, how do you park the drug that's going to attack this that's going to either kill it or enhance it?
You need to know what the shape of it.
So, the way they do is one by one.
So, they so they created this competition to be like, "Can anyone use computers to predict the protein folding cuz doing this manually is untenable."
And for years, if you look at the graph, it was like, you know, like kind of this like 20%, 30% prediction accuracy for like a decade.
So, Demis decides he's like, "This is what we're going to do.
We're going to throw our resources behind this."
And the first time they do it, they win the competition, but they're like, "Great, we're trying to go to the moon, and we just have like the tallest ladder."
Like the ladder doesn't get you to the moon.
And so, they were actually incredibly disappointed.
And he's like, "This was like a bitter taste of we really tried, we won, but not by enough to even solve the protein We're like we're here to solve the protein folding problem, not win the competition.
And to solve it, you need 90% plus accuracy."
And he describes this like the next year where they basically were like, "So, we went back to the drawing board, try to come up with new ideas."
And he I thought it was a cool CEO moment.
So, he was like, "I know when you need to come up with a creative idea, you can't force it.
Like squeezing it doesn't make creativity come out when you just push the team. We need an answer now.
Like that's not going to get the best idea."
>> because that's the opposite of what I would think in there have been people who would say constraints are the answer.
So, they used constraints, but what they didn't do was basically like put everybody into fight or flight mode.
Because when you're in fight or flight, it's kind of like why your best ideas come to you when you're in the shower or when you're relaxed or when you when you're asleep or when you're on a walk.
Because the brain like you have two modes.
One is executive mode where you're doing tasks, and that's good at doing tasks, but it's not good at making new connections between existing fuzzy data.
Dude, that's so interesting because this is how Henry Ford so uh Henry Ford um uh one of the thing basically there's an engine block.
So, it's a block of of metal, and you put cylinders in there, and that's how um a car combustible engine works, but before that was one block, it used to be two blocks, and it kept breaking.
Imagine two blocks and they screwed things together, and it was it was holding them back from taking over the world.
Henry Ford got a team of four engineers of the company of thousands of people, and he goes he the story is that he brought them to a small office.
He goes, "This is you guys' workshop."
And they're like, "What are we doing?"
He's like, "You see that big-ass block of metal?
Uh figure out how to put four holes in there and four four four pistons and make it work."
And they're like, "Henry, sir, that's impossible."
He goes, "I'll see you guys in a quarter."
And apparently the story is is that he went back uh like eight quarters in a row.
So, it was something like 2 years, and then finally they got it. But it took 2 years.
But he did allow them "This is four of you. This is your job.
Just figure it out and let me know." Exactly.
And this is also how if you read about like Steve Jobs with the he was like, "No keyboard on the phone."
And they're like, "But the BlackBerry had a keyboard.
Like you got to write emails."
No keyboard on the phone.
And they're like, "But how would we the accuracy this I mean screens today don't" He's like, "No keyboard on the phone."
And so, then they had to go invent multi-touch and figure it out.
But so, he gave them the constraint the you got to do it in this these are the constraints, but then I give you the time to go explore and figure out like which path might work. >> That's interesting.
Uh and they they also did this with the game thing, by the way.
When they did the Go thing, the first one was like again trained on 100,000 games.
Then they created AlphaZero where they said, "Now try to make it win with no prior human knowledge."
Cuz he's like, "If we're ever going to do new novel things, you got to assume we we're not going to have a database of 100,000 good humans at doing this to use." And so, they did.
They created AlphaZero which could win in chess and Go with just by playing itself like 10 million times or whatever. It figured it out.
And so, similarly here they're like, "You got to go back to the drawing board."
He described he goes, "First, I'm going to give them the constraints.
Second, I'm going to let them be creative and try to go go go to the drawing board, figure out multiple different possible ways this might work."
He goes, "And then when they pick one," he goes, "I know this is when it's time to push."
He goes, "Because first, we will get worse than we were before.
Then after some time, we'll pick an approach and we'll get right back close to where we were before."
He goes, "And that's when it's time to push.
I've seen it so many times before, and we'll explode through."
And I was like, "That's pretty dope how he kind of had developed judgment on the scientific process and the creative process enough to know when do you push and when do you not push."
>> Dude, that's so great.
We're learning all these techniques, and I'm putting it all together.
Hermosi had this cool thing that he said when I talked to him once.
He was like, "Basically, I've noticed that when you start something new, the results go down 20% right off the bat.
So, if you're training your sales team on something new, their conversion rate is actually going to drop from 50% down to you know, it'll drop 20 20%. So, down 10 points.
But eventually, it will go up if you pick the right thing.
And so, the question is basically make sure you pick the right thing because if it's going to go down 20%, that means you need it to double its improvement in order for it to be worth it.
So, you pick the right thing.
Otherwise, you're just back to square one, and you went down 20% for a quarter. Right.
And so, knowing that these J-curve progress things exist is important cuz the amateur would panic.
The amateur would would not go forward and >> my biggest learning this year running a company.
It was like expect new things to suck or bring down bring everything down.
Therefore, make your project selection perfect >> or right or high high quality. Right.
And so, he anyways, they end up crushing the thing, and um they they show kind of like how they did it.
They they end up getting 90% prediction accuracy, and they basically solved the single protein folding question.
Now, there's also like multi-protein, and there's like variations, and there's like all these other Now now they moved on to harder things, but it's pretty crazy that the the line graph was like, you know, 20-30%, 20-30%, and then went to 90 in 1 year when they like went back to the drawing board and figured it out.
And how ecstatic they were.
They're like, "Yo, this this just changed the world.
People don't realize this yet, but this just changed the world.
And it's reminded me of your inflection thing, which we should say what what what is your describe your inflection thing for entrepreneur.
I think it's one of the best like axioms or principles you have on entrepreneurship.
Yeah, basically and and and I I didn't invent this.
I think it was Maples, Mike Maples I think.
I don't remember exactly, but um basically the idea is that in order for a lot of like big breakthrough ideas to truly happen, not like small businesses that make tens of millions of dollars, but like culture-changing companies, you basically have to have inflections.
And so there's a handful of inflections that matter.
There could be regulatory inflections.
So during COVID uh BetterHelp and all these telemedicine things existed because we changed the rules on who who doctors can serve.
It could be um cultural inflections.
So like the Me Too movement, that changed a a bunch of stuff.
Or it could be why does Uber exist?
Well, there was a technology technology inflection.
Everyone now had a cell phone that had GPS on their phone, therefore they could call an Uber wherever they they were.
And there's about five or six different categories of inflections and you have to spot the inflections to know what's actually worth like going after because that you need an inflection in order for a right culture-changing company to exist.
And so I think this I think this AlphaFold stuff or figuring out the protein folding is is a massive inflection.
And I didn't really know what the businesses were around this, but I kind of like Googled afterwards.
I was like, you know, I was talking to Croc and asking it about this.
So there's some pretty cool companies.
I didn't realize first of all Google has their own company they spun out from this. So Isomorphic Labs.
So basically Google has spun out this company that is basically trying to cure all disease. That's the mission. No big deal.
And their thought process is like, well, with AI we can, you know, from first principles change the way that drug development and discovery works.
Cuz if we can predict how the proteins fold, then we can have a way higher hit rate on the targets we design with the drugs, then we should be able to simulate if it's going to work with it before we even get to clinical trials.
We should be able to run, you know, hundreds of thousands of simulations to see how effective this can be get the probability of success higher so that when we enter a trial, we have a way higher hit rate.
And this company, by the way, their first round of funding was $600 million um to to as they spun it out of Google and DeepMind.
And Demis is the CEO, I think, of Isomorphic Labs.
And so like, you know, there's a there's a world where Google becomes the drug company that, you know, cures like right now they're working on malaria and like these different things.
>> CEO of DeepMind as well? >> Yeah. Wow.
The H1 on isomorphiclabs.
com, the headline is solve all disease.
We're entering a new era of drug discovery, one where the frontier of AI can unlock deeper insights, faster breakthroughs, and life-changing medicines.
If I was uh doing a Sarah's List episode right now, Isomorphic Labs would be one of those where I'd be like, go go be a PR person there.
Go go be a junior account manager there.
Yeah, there's [clears throat] a cafeteria workers, yeah, you guys have cafeteria >> show up and you say, "Hey, I I'm the best coffee bringer to your desk ever. Give me a job here.
I will find ways to be useful every single day, whether it's in any job you have, I need to be at this company."
Cuz I I can't can't think of a you know, how many companies have a more noble mission, but actually a shot of cracking it cuz there's a new tech vector to to go chase.
>> So um how does the the the documentary like where where does he leave it?
The end is weird because it's actually like the beginning they're still in the beginning stages of what they're doing. Right?
So it's like they end the documentary, but it's like the AI stuff is just starting to work.
So they end it with after the AlphaFold thing, people like all these sci like it was a big thing in the science community and so all these researchers and drug companies were like, "Hey, can we get access to this?
Cuz if we know protein structures, this will be tremendously helpful."
So they're like, "Oh, we should set up like a service where you can request a protein and then we tell you how it's folded and then blah blah blah."
And then Demis was like, "Can we just fold all the proteins?"
And they're like, "What?"
And he's like, "How long would it take to fold all proteins known in existence?"
And they're like, "Uh we could do that in like 2 months."
He's like, "Well, why don't we do that?
Let's fold them and give it all away."
And he's like, "Let's just make it open for anybody.
Let's go run the computer, fold all the proteins, give it all away."
And so that's what they did at the end.
They folded 200 million plus basically every known protein in existence.
And they made it available and the end is basically like researchers from around the world showing up on their Google Analytics like logging in.
They're like, "We have 100,000 current users.
We have, you know, they now have 3 million users."
And that's everyone from like someone in Africa running, you know, a small lab to universities to Eli Lilly who are all using them to uh to to be smarter and better about how they do, you know, medicine.
Dude, how are all the guys who work at Isomorphic Labs and DeepMind and Demis, how are they all not like Andrew Tate-looking dudes?
Like the most tan like jacked dudes ever?
Cuz like if you can cure >> Are they taking peptides?
If you can cure all disease, like how are they not like the hottest people on Earth?
>> [laughter] >> I think the way you become that smart is you don't care about stuff like that. Right?
Like No, you become that smart because you were bullied.
But now you're going to seek you're going to seek revenge.
And the issue with bullying going away is that none of these nerds are going to exist, you know what I mean? >> Right.
>> [laughter] >> It's like I know we're getting close with Demis is 6'4" and like, you know, has visible lats.
>> [laughter] >> Yeah, why does he not look like Adonis? That's my question.
I think when Larry I don't pay attention to the news too much, but when Larry Ellison and Masayoshi Son and Trump and Altman did this thing where it was like, you know, a hundred trillion dollars or some like ludicrous number.
They it was under the premise of like this is going to cure disease.
And Larry Ellison, I do know that Larry Ellison's in his 80s, I think, or close Yeah, he's looking good, Larry.
or close too and he's looking great.
And his wife like is like a 30-year-old, but for some reason they don't look like that much of a different age even though there is literally a 50-year difference.
And it was under the premise of like we, you know, Larry's interested in solving death and therefore we must do that.
Whenever I hear that I just think that's just words that are meaningless, but now that I know a little bit more about the topic just from you now, is that actually a legitimate thing?
Well, I'm glad you're asking me because as a pre-med student I'm I'm clearly an expert at this.
I only took one class on this 15 years ago.
I only took one class on this 15 years ago.
>> [laughter] >> Somebody got a C in physics had to repeat had to repeat in the summer.
It's like on Instagram with people report like you see like Instagram videos of people with their children and like the kids like on an iPad or are screaming and someone's like, "Well, as a mother I could never."
It's like, "Dude, you mean as a human being like I don't care, okay?
You don't like as a mother does not mean that you are right."
>> [laughter] >> Shots fired. Mom, not special.
>> Yeah, as a as a father, like brother, I everyone's a father, okay? I don't care.
>> [laughter] >> There's a line where they're talking to like one of the OGs of artificial intelligence and they were saying like, "You know, what are our predictions?"
And he goes, "It's hard to predict what's going to happen as we make this intelligence into super intelligence."
He goes, "It's like asking a gorilla to explain Einstein's theory of relativity."
And when I heard that I go, "Oh yeah, we're we're they're going to be we're going to be the gorillas out of this whole thing, right?"
Because clearly if you're making intelligence that's smarter than any human, you're creating, you know, the next race.
It's like to an animal, they if they just saw a human at first, they'd be like, "Ah, looks kind of skinny.
Uh they got a little funny little extra appendage on their hand, you know, all right, cool.
They they walk upright, ooh cool, but they're pretty slow actually."
And then you're like, fast forward, you know, 200 years and, you know, you see the Blue Angels flying above you. 200 years?
>> [laughter] >> Yeah, I don't know. Just a lot of time. 2,000 years maybe or 20. I don't I don't know.
Speaking of gorillas, we are a few brain cells away from gorillas.
>> [laughter] >> But just like what humans have done is like kind of incomprehensible to any to our closest animal, you know, relative, that's what's going to happen here, which I think is pretty crazy.
Uh I don't know if you listen to Mark Manson. He's he's the man.
Basically he wrote this he did a podcast.
I think it was his second most recent one.
It's about it's a Q&A maybe.
Uh finding your purpose, failing better, and the AI future.
So that was it was basically like an end-of-the-year Q&A, which we actually did as well.
And he tells the story about how he built an AI product recently.
And so someone asked him, "What do you think about the future of AI?"
And he was like, "Well, I just built an AI product and what I I realized a few things.
One, AI is amazing in that it's better than 95% of people at certain things, but the vast majority of value created by in in the world is created by people who are 99.
9% better at people than human things.
Like you still need these experts and AI can be great, but it's not an expert."
But then he also said, "You know, there's maximalists who think that AI is going to come really soon and take over the world and we're all going to be worthless.
And there's other people who think that, you know, it might happen over many decades, but we're probably going to be fine."
And he was like, "I tend to be in that category."
And the reason being is that when a lot of people think about uh AI, they think that it's just going to take all of our jobs and we're not going to work anymore.
But human desire is not fixed.
And when you're thinking about uh AI, often times people think desire is fixed.
Meaning once you hurt hit a certain level of productivity, you will not do stuff."
And he's like, "That's just false.
For example, if we look at the Industrial Revolution, people said the same thing when uh certain stuff started happening.
And then you look at like the Victorian area where we started getting electricity, things like that, people made the same claim of we're not going to work again.
We need universal income and all this stuff."
And he's like, "Humans just always want more.
And because of that, I don't think that there's ever going to be a point where we are useless.
It's just going to be different."
And I thought that was a really great perspective on it.
And that's one of the first times I've heard a perspective on it other than maybe Dharmesh talking about it where I felt calmer where I was like we're just going to human desires is not fixed. We will evolve. Mhm. Yeah, it's interesting. I don't know.
Have you read this There's this book I haven't read it yet, but it's called If Anyone Builds It, Everyone Dies.
>> [laughter] >> I don't think I'm going to be reading that one. Yeah, yeah.
I mean it's a crazy documentary and I think you know what My meta takeaway is I love that they were filming this the whole time.
I'm glad that smartphones and video and these video platforms are so popular now that because imagine 10 years from now.
I think we're going to have 10 times the number of like documentary behind the scenes building a type of things.
Right now it feels like a fluke whenever this happens.
For example, we did a podcast about the Kanye documentary.
And the craziest thing about the Kanye documentary is not about Kanye.
It's about the guy who just decided, "You know what?
I'm going to just film this young guy in Chicago over a 10-year period and I cuz I think he's got something here, which is like one of the greatest calls ever.
Um you know, before Kanye was Kanye this guy started filming.
And I think we were lucky that that ever happened.
That's like a a lottery ticket level win for society that that that that guy just decided to film this religiously when there was no reason to believe that that he should do that.
Conor McGregor did this on his way up and he's like, "I'm going to be the best.
You know, like I Yeah, I'm a plumber now and there's never been an Irish champion, but I'm going to do it."
And he basically started a documentary at that and because of that you get this incredible look at the like what it was like on the come up.
It's incredibly inspirational whenever this happens.
I'm just glad that this that they did this and I'm I hope more people do this.
That That was my like big picture takeaway was really not even about DeepMind itself.
And that I was going to say that that um like the need for like human craft goods.
So for example, you could buy anything you want, but like some people still want like the handmade [ __ ] from Italy and they want to know the story behind it.
And when you were talking about the story about him playing the Chinese guy and the Korean guy, like there's still a human is half of the story and arguably like I mean not arguably it was is necessary to the story.
We are still drawn to stories and story is in my head is sort of an analogy to like where humans fit into this thing.
We're still drawn to these like human elements of all of these stories, which makes me believe like well, we have to be part of this experience and like we're not going to be completely outsourced because it's what the most interesting part is that this genius guy has called his shot this whole time and has been interested in this for years.
Like that's actually the most compelling part. Yeah, yeah.
Although, you know, I think you don't want to be relegated to like well, we'll still make handmade goods.
It's like that's the 1% 99% is the is the mass manufacture things.
You also don't want it to be where well, we'll always be interested in human like entertainment and it's like but everything else will be done by the AI.
>> No, but I don't mean that, but I mean like >> You know, like when you fly on a plane you're not like, "Can I get the one where the pilot's doing all the work?" Right?
You're like, "Okay, cool.
This is like run by a computer that's way safer than a pilot." Great.
I'm There's I'm glad there is a pilot, but like the computer could fly. I'm I'm cool with that.
>> think that I'm not I I mean part of me is nervous, but I do like um well, a lot a big part of me is actually nervous, but Most [laughter] of me.
I was like it's like it's like when people say like, "Well, some people say uh some people say uh it's not a big of a deal." Most don't.
But some Some few people got their head in the sand. Most don't, but some do.
Uh I just think that like we still are going to play an important role and like >> [laughter] >> like I I'm not too worried, although I am very worried.
>> [laughter] >> There's also this funny thing that happened on the documentary point.
Did you see the founder of Robinhood talking about his documentary? No, what did he say? So I didn't know this.
Vlad from Robinhood when Robinhood was getting started, he put up a Kickstarter saying, "Hey, I'm going to try to build this company that's going to change the way the financial markets work.
And if you guys fund $10,000, we'll film it cuz how cool would it be to see Steve Jobs building Apple?
How cool would it be to have seen, you know, these guys building Google?
Like that's what we're going to do."
And then it didn't hit its Kickstarter goal and they didn't do it.
>> [laughter] >> Isn't that crazy?
The Kickstarter project's still up. You can see the trailer.
By the way, I can see why it didn't get funded.
The trailer was garbage, but like with the idea and him being like He's like, "Yeah, like in hindsight I was That was right.
That would have been awesome.
But we didn't hit the 10K.
We only got to two $3,000 donated, so we didn't do it." So funny. Oh my god.
>> [laughter] >> I mean Did he actually compare himself to Steve Jobs or are you saying like >> I I I don't remember what he said in the Kickstarter part, but I think he's not comparing himself.
He's just kind of like trying to get you excited about why should you care about this company you've never heard of.
And he's like, "Well, imagine if the great companies had had this at the beginning.
You would have wanted that, right? You know?" >> god, that's so funny. He called his shot.
He just didn't like Nobody cared.
>> [laughter] >> Yeah, but think like um I've talked about this.
I love doing home movies.
So I I try to like every day I take like a 3-minute video of my family of us doing something and I have [clears throat] it on like a secret YouTube channel. What's it called?
>> [laughter] >> Sam's Super Stop Secret Channel Don't Look.
>> [laughter] >> But all the videos are unlisted.
You couldn't even see if you wanted to.
But um cuz a YouTube short can be 3 minutes now.
And so I do I'm doing three cuz the problem with a lot of these videos that you take with your family or with your friends, they're just like 10 seconds and you're like telling your friend like, "Wait, repeat. Hold on. Do it again."
versus like here we are like remember when you were when you were a kid and your dad's like, "Here we are Christmas morning." >> We're doing this. And those are the best.
Those are the best videos.
Uh and so thank god like we have these phones cuz that's really what a video should be.
It's like a 3-minute to 5-minute video of someone narrating saying what's going on and you're not No one's performing.
Versus now whenever I pull my phone out, it's always like, "Wait, hold on.
Tell me that joke again."
>> [laughter] >> How do you feel?
Are you um So I definitely land on the optimistic side.
I think he's a badass and I loved hearing his story.
I think it's super mission-driven.
I think it's super cool that these guys believed 20 years before anybody else.
I think it's super cool they filmed the thing.
I think that the breakthroughs they're doing I I like seeing use of AI that's not all the same, which is like today the chat GB whoa the chat GPT experience is so dominant that it feels like that's what AI is.
And it's kind of like early internet like getting online and being like AIM or AOL news.
Like this is the internet.
And it's like, "No, dude.
There's so much more that's going to come."
That's how I felt when I heard more about the protein folding stuff and how they did the game stuff and how that's going to apply to all these other domains.
And I walked away being like, "Oh man, if I was kind of young and just trying to figure things out.
If you're high potential and you don't know where to go like I got two words that'll probably make you a billion dollars. Computational biology.
Just go there and just go play around.
If you're an entrepreneur, like forget building a GPT wrapper, build an AlphaFold wrapper.
I think you could build multi-billion dollar like what Cursor did.
Cursor basically said They didn't make the model.
They were like, "Let's take Claude, but we'll just wrap this in a tool that programmers can use that will be very useful for programmers.
Go do that for pharmaceutical companies.
Go do that for research labs.
Go create Oh or you realize that with protein folding people are going to want to test protein uh like the actual protein synthesis in the real world.
That demand is going to go up 100x.
Go create wet labs and just do the tests for these for the people who are using computers to come up with their hypotheses.
That demand is going to go 1,000x.
I was like, "Man, there's so much opportunity for anybody who wants it." I got two words for you.
I thought it was going to be like, "Suck it."
But it was >> [laughter] >> com- computational biology.
You You took me You led me down a path.
I thought you were going one way not the other way. That was great.
>> [laughter] >> Um this was a great episode. All right, that's it. That's the pod.