At the end of 2022, our team at a16z asked dozens of partners across the firm to spotlight one big idea that startups in their fields could tackle in 2023. Emerging from this exercise came 40+ builder-worthy pursuits for the year, ranging from entertainment franchise games to precision delivery of medicine to small modular reactors, and of course loads of AI applications. In our 2-part series, we’ll be covering 12 of these big ideas with the partners that shared them. Here in part 2, we’ll cover Fintech, American Dynamism, and Bio & Health. Listen in as we chat with Anish Acharya, Angela Strange, Michelle Volz, Ryan McEntush, Vijay Pande, and Julie Yoo. And for the full list of 40+ ideas, check out the full article: https://a16z.com/2022/12/15/big-ideas-in-tech-2023/ Topics Covered: (0:00) Intro (1:12) GPT Unlocks Credit Counseling - Anish Acharya (10:31) Compliance as a Competitive Advantage - Angela Strange (23:48) Small Modular Reactors Advance the Nuclear Renaissance - Michelle Volz (34:38) Overhauling the Space Supply Chain - Ryan McEntush (46:36) The Biggest Company in the World - Vijay Pande (53:29) The Value-Based Care Stack - Julie Yoo Resources: - https://a16z.com/2022/11/02/america-space-age/ - https://a16z.com/2022/11/11/the-biggest-company-in-the-world/ - https://a16z.com/2021/01/08/the-new-tech-stack-for-virtual-first-care/ Stay Updated: Find us on Twitter: https://twitter.com/a16z Find us on LinkedIn: https://www.linkedin.com/company/a16z Subscribe on your favorite podcast app: https://a16z.simplecast.com/ Follow our host: https://twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.
This conversation between the members of a16z's bio team -- including general partners Jorge Conde and Vijay Pande; Malinka Walaliyadde; and Jeffrey Low (the interviewer) -- takes a quick pulse on where we are with when bio becomes more like engineering. Especially given the announcement of our second bio fund, this episode of the a16z Podcast covers everything from the broader trends at play to some specific areas of interest... as well as what types of entrepreneurs may bring us forward into the new Century of Biology.
In this episode, Vijay Pande and Daisy Wolf of a16z Bio + Health make a provocative case for why technologists—not just medical professionals—are key to reinventing healthcare. They argue that to transform a sector representing 20% of U.S. GDP, innovation must move beyond curing diseases toward tackling healthcare’s broken systems. By likening the healthcare industry to a logistics challenge, Vijay and Daisy outline how technologists can leverage their expertise in consumer engagement, operational efficiency, and AI to drive the next frontier of health innovation. They also explore high-impact opportunities like improving patient experiences and deploying AI for behavioral change at scale. If you’re ready to explore new paths in healthcare, this episode is essential listening for understanding the powerful role technologists can play in shaping its future. Resources: Find Vijay on X: https://x.com/vijaypande Find Daisy on X: https://x.com/daisydwolf Learn more about a16z Bio+Health: https://a16z.com/bio-health/ Learn more about Raising Health: https://a16z.com/podcasts/raising-health/ Stay Updated: Find a16z Bio+Health on LinkedIn: https://www.linkedin.com/showcase/a16z-bio-health/ Find a16z Bio+Health on X: https://x.com/a16zBioHealth Subscribe on your favorite podcast app: https://a16z.com/podcasts/raising-health/ Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.